Results 111 to 120 of about 2,800 (262)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

On List Extensions of the Majority Edge Colourings

The Electronic Journal of Combinatorics
We investigate possible list extensions of generalised majority edge colourings of graphs and provide several results concerning these. Given a graph $G=(V,E)$, a list assignment $L:E\to 2^C$ and some level of majority tolerance $\alpha\in(0,1)$, an $\alpha$-majority $L$-colouring of $G$ is a colouring $\omega:E\to C$ from the given lists such that for
Pawel Pekala, Jakub Przybylo
openaire   +2 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Research on citrus grading system based on machine vision

Systems Science & Control Engineering
In response to the growing demand for standardized fruit quality in the market, a citrus grading system utilizing machine vision technology is designed.
Miao Xu, Xuan Zhang, ChangJun Zhan, JianYu Ge, Hua Yang   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

JUST CHROMATIC EXCELLENCE IN FUZZY GRAPHS

Journal of New Theory, 2017
Abstaract−Let G be a simple fuzzy graph. A family Γf= {γ, γ2, . . . , γk} of fuzzy sets on a set V is called k-fuzzy colouring of V = (V, σ, µ) if i)∪Γf= σ, ii) γi∩ γj= ∅, iii)for every strong edge (x, y)(i.e., µ(xy) > 0) of G min{γi(x), γi(y)} = 0 ...
- Dharmalingam, Udaya Suriya
doaj  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

On Generalised Majority Edge-Colourings of Graphs

The Electronic Journal of Combinatorics
A $\frac{1}{k}$-majority $l$-edge-colouring of a graph $G$ is a colouring of its edges with $l$ colours such that for every colour $i$ and each vertex $v$ of $G$, at most $\frac{1}{k}$'th of the edges incident with $v$ have colour $i$. We conjecture that for every integer $k\geq 2$, each graph with minimum degree $\delta\geq k^2$ is $\frac{1}{k ...
Pawel Pekala, Jakub Przybylo
openaire   +3 more sources