Results 61 to 70 of about 2,800 (262)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Wild edge colourings of graphs

open access: yesJournal of Symbolic Logic, 2004
AbstractWe prove consistent, assuming there is a supercompact cardinal, that there is a singular strong limit cardinalμ, of cofinalityω, such that everyμ+-chromatic graphXonμ+has an edge colouringcofXintoμcolours for which every vertex colouringgofXinto at mostμmany colours has ag-colour class on whichctakes every value.The paper also contains some ...
Mirna Dzamonja   +2 more
openaire   +5 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Vertex colouring edge partitions

open access: yesJournal of Combinatorial Theory, Series B, 2005
Suppose that the edges of a graph are assigned labels from a \(k\)-set, or equivilently, the edges are partitioned into \(k\) parts. Each vertex \(v\) has an associated multiset \(X_v\) consisting of the labels on its incident edges. The partition is a (proper) vertex coloring if for every edge \(uv\), \(X_u \neq X_v\).
Louigi Addario-Berry   +3 more
openaire   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

On (k1A1, k2A2, k3A3)-Edge Colourings in Graphs and Generalized Jacobsthal Numbers

open access: yesAnnales Mathematicae Silesianae
In this paper we introduce a new kind of generalized Jacobsthal numbers in a distance sense. We give the identities and matrix representations for them and their connections with the Fibonacci and the Pell numbers. We also describe the interpretations of
Piejko Krzysztof, Trojnar-Spelina Lucyna
doaj   +1 more source

The power of many colours

open access: yesForum of Mathematics, Sigma
A classical problem, due to Gerencsér and Gyárfás from 1967, asks how large a monochromatic connected component can we guarantee in any r-edge colouring of $K_n$ ?
Noga Alon   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Vertex-Colouring Edge-Weightings

open access: yesCombinatorica, 2007
A weighting w of the edges of a graph G induces a colouring of the vertices of G where the colour of vertex v, denoted cv, is $${\sum\nolimits_{e \mathrel\backepsilon v} {w{\left( e \right)}} }$$. We show that the edges of every graph that does not contain a component isomorphic to K2 can be weighted from the set {1, . . .
Addario-Berry, L   +4 more
openaire   +1 more source

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