Results 41 to 50 of about 138,912 (199)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Let $S=K[x_1,\dots,x_n]$ be the polynomial ring over a field $K$ and $I\subset S$ be a squarefree monomial ideal generated in degree $n-2$. Motivated by the remarkable behavior of the powers of $I$ when $I$ admits a linear resolution, as established in [11], in this work we investigate the algebraic and homological properties of $I$ and its powers.
Ficarra, Antonino, Moradi, Somayeh
openaire +4 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Regularity and $h$-Polynomials of Edge Ideals [PDF]
The Electronic Journal of Combinatorics, 2019 For any two integers $d,r \geqslant 1$, we show that there exists an edge ideal $I(G)$ such that ${\rm reg}\left(R/I(G)\right)$, the Castelnuovo-Mumford regularity of $R/I(G)$, is $r$, and $\deg h_{R/I(G)}(t)$, the degree of the $h$-polynomial of $R/I(G)$, is $d$.
Takayuki Hibi +2 more
openaire +3 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Construction of Cohen–Macaulay Binomial Edge Ideals [PDF]
Communications in Algebra, 2013 We discuss algebraic and homological properties of binomial edge ideals associated to graphs which are obtained by gluing of subgraphs and the formation of cones.
Rauf A., RINALDO, GIANCARLO
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Clinical Case Reports, 2023 Key Clinical Message Three‐dimensional multiplanar analysis and real‐time three‐dimensional guidance using transesophageal echocardiography can help to identify and access the ideal position for transseptal puncture even in the presence of atrial septal ...
Hiroyuki Tabata +3 more
doaj +1 more source
Communications in Algebra, 2012 Let P = k[x_1, ..., x_n] be the polynomial ring in n variables. A homogeneous ideal I of P generated in degree d is called Gotzmann if it has the smallest possible Hilbert function out of all homogeneous ideals with the same dimension in degree d. The edge ideal of a simple graph G on vertices x_1, ..., x_n is the quadratic square-free monomial ideal ...
openaire +2 more sources
Binomial Edge Ideals with Quadratic Gröbner Bases [PDF]
The Electronic Journal of Combinatorics, 2011 We prove that a binomial edge ideal of a graph $G$ has a quadratic Gröbner basis with respect to some term order if and only if the graph $G$ is closed with respect to a given labelling of the vertices. We also state some criteria for the closedness of a graph $G$ that do not depend on the labelling of its vertex set.
CRUPI, Marilena, RINALDO, GIANCARLO
openaire +4 more sources