Results 81 to 90 of about 138,912 (199)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

A Method for Assessment of Segmentation Success Considering Uncertainty in the Edge Positions

EURASIP Journal on Advances in Signal Processing, 2006
A method for segmentation assessment is proposed. The technique is based on a comparison of the segmentation produced by an algorithm with an ideal segmentation. The procedure to obtain the ideal segmentation is described in detail.
Usamentiaga Rubén, García Daniel F, López Carlos, González Diego   +3 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Computing degree based topological indices of algebraic hypergraphs

Heliyon
Topological indices are numerical parameters that indicate the topology of graphs or hypergraphs. A hypergraph H=(V(H),E(H)) consists of a vertex set V(H) and an edge set E(H), where each edge e∈E(H) is a subset of V(H) with at least two elements.
Amal S. Alali, Esra Öztürk Sözen, Cihat Abdioğlu, Shakir Ali, Elif Eryaşar   +4 more
doaj   +1 more source

Some Remarks on the Annihilating-Ideal Graph of Commutative Ring with Respect to an Ideal [PDF]

Mathematics Interdisciplinary Research
‎The graph $ AG ( R ) $ {of} a commutative ring $R$ with identity has an edge linking two unique vertices when the product of the vertices equals {the} zero ideal and its vertices are the nonzero annihilating ideals of $R$‎.‎The annihilating-ideal graph ...
Zahra Mahmudiankoruie, Mohammad Hasan Naderi   +1 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Functional Connectivity Linked to Cognitive Recovery After Minor Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Patients with minor stroke exhibit slowed processing speed and generalized alterations in functional connectivity involving frontoparietal cortex (FPC). The pattern of connectivity evolves over time. In this study, we examine the relationship of functional connectivity patterns to cognitive performance, to determine ...
Vrishab Commuri, Isabella Dallasta, Ciaran Stone, Sophia Girgenti, Neda Gould, Rafael H. Llinas, Jonathan Z. Simon, Elisabeth Breese Marsh   +7 more
wiley   +1 more source

Koszul binomial edge ideals

Forum of Mathematics, Sigma
The study of Koszul binomial edge ideals was initiated by V. Ene, J. Herzog, and T. Hibi in 2014, who found necessary conditions for Koszulness. The binomial edge ideal $J_G$ associated to a finite simple graph G is always generated by quadrics ...
Adam LaClair, Matthew Mastroeni, Jason McCullough, Irena Peeva   +3 more
doaj   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source