Results 61 to 70 of about 279,742 (250)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The novel resolvability parameter, local edge partition dimension of graphs

Open Journal of Discrete Applied Mathematics
In this paper, we introduce a new resolvability parameter named as the local edge partition dimension \((LEPD)\) of graphs. The local edge partition dimension \((LEPD)\) makes a specialty of partitioning the vertex set of a graph into awesome ...
Sikander Ali, Furqan Ahmad, Muhammad Kamran Jamil   +2 more
semanticscholar   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

A valent-based metric framework for analyzing intuitionistic fuzzy graphs in uncertain environments

Ain Shams Engineering Journal
This paper introduces a new notion of distance in intuitionistic fuzzy graphs, termed the Valent distance, which incorporates the degrees (valences) of both vertices and edges.
J. Komathi, D. Meiyappan, K. Anitha
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

On metric dimension of edge comb product of vertex-transitive graphs [PDF]

Transactions on Combinatorics
Suppose finite graph $G$ is simple, undirected and connected. If $W$ is an ordered set of the vertices such that $|W| = k$, the representation of a vertex $v$ is an ordered $k$-tuple consisting distances of vertex $v$ with every vertices in $W$. The set $
Tita Maryati, Dindin Sobiruddin, Maifalinda Fatra, Fawwaz Hadiputra   +3 more
doaj   +1 more source

On Symmetrical Convex Polytopes and their Edge Resolvability

Journal of Combinatorial Mathematics and Combinatorial Computing
The \textit{metric dimension} of a graph Γ = ( V , E ) , denoted by dim ( Γ ) , is the least cardinality of a set of vertices in Γ such that each vertex in Γ is determined uniquely by its vector of distances to the vertices of the chosen set.
S. Sharma
semanticscholar   +1 more source

A new edge detection approach via neutrosophy based on maximum norm entropy

Expert systems with applications, 2019
It is a quite important step to find object edges in applications such as object recognition, classification and segmentation. Therefore, the edge detection algorithm to be used directly influences the performance of these applications.
E. Sert, Derya Avcı
semanticscholar   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The Metric Dimension of Theta Graph

Jurnal Diferensial
Let $ G = (V, E) $ be a connected graph with vertex set $ V(G) $ and edge set $ E(G) $. For any two vertices $ u $ and $ v $ in $ G $, the shortest path distance between $ u $ and $v$ is denoted by $d(u, v)$.
Deddy Rahmadi, Wakhid Fitri Albar
doaj   +1 more source