Results 81 to 90 of about 1,569,447 (281)
Cooperative wireless edge caching with relay selection [PDF]
2017 IEEE International Conference on Communications (ICC), 2017 Relay selection is a simple yet effective means to improve the reliability and coverage of wireless cooperative networks. However, it suffers from inefficient use of the available bandwidth resources. This paper introduces the use of content caching at relays in order to tackle this problem and improve the performance of relay selection.
Psomas, C. +5 more
openaire +3 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Hangkong gongcheng jinzhan, 2020 The main failure mode of composite stiffened panel is buckling. In order to ensure the safety of the structure and effectively reduce the weight of the structure, it is necessary to systematically study the boundary conditions and the width of the load ...
GAO Wei, YAO Xionghua, WANG Yunfeng
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The mechanism of variability in transcription start site selection
eLife, 2017 During transcription initiation, RNA polymerase (RNAP) binds to promoter DNA, unwinds promoter DNA to form an RNAP-promoter open complex (RPo) containing a single-stranded ‘transcription bubble,’ and selects a transcription start site (TSS).
Libing Yu +5 more
doaj +1 more source
Lattices of Graphical Gaussian Models with Symmetries
, 2011 In order to make graphical Gaussian models a viable modelling tool when the number of variables outgrows the number of observations, model classes which place equality restrictions on concentrations or partial correlations have previously been introduced
Andersen +15 more
core +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Distributed Linear Precoding and User Selection in Coordinated Multicell Systems
, 2015 In this manuscript we tackle the problem of semi-distributed user selection with distributed linear precoding for sum rate maximization in multiuser multicell systems.
Castañeda, Eduardo +3 more
core +1 more source