Results 61 to 70 of about 50,367 (275)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Approximating Edit Distance Efficiently [PDF]
45th Annual IEEE Symposium on Foundations of Computer Science, 2004 Edit distance has been extensively studied for the past several years. Nevertheless, no linear-time algorithm is known to compute the edit distance between two strings, or even to approximate it to within a modest factor. Furthermore, for various natural algorithmic problems such as low-distortion embeddings into normed spaces, approximate nearest ...
Z. Bar-Yossef +3 more
openaire +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Evaluating Automatic Detection of Misspellings in German [PDF]
Language Learning and Technology, 2008 his study investigates the performance of a spell checker designed for native writers on misspellings made by second language (L2) learners. It addresses two research questions: 1) What is the correction rate of a generic spell checker for L2 ...
Anne Rimrott, Trude Heift
doaj
A Binary Integer Programming model for computing DNA Sequence Alignment [PDF]
Al-Rafidain Journal of Computer Sciences and Mathematics, 2010 DNA Sequence Alignment is an important problem in computational biology and is useful for comparing genomes and finding genes, for determining evolutionary linkage of different biological sequences.
Nawar Qubat
doaj +1 more source
Online Pattern Matching for String Edit Distance with Moves
, 2014 Edit distance with moves (EDM) is a string-to-string distance measure that includes substring moves in addition to ordinal editing operations to turn one string to the other.
D. Shapira +7 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
JMIR Medical Informatics, 2021 BackgroundClinical terms mentioned in clinical text are often not in their standardized forms as listed in clinical terminologies because of linguistic and stylistic variations.
Kate, Rohit J
doaj +1 more source
Convex Graph Invariant Relaxations For Graph Edit Distance [PDF]
, 2019 The edit distance between two graphs is a widely used measure of similarity that evaluates the smallest number of vertex and edge deletions/insertions required to transform one graph to another.
Candogan, Utkan Onur +1 more
core +1 more source
Journal of Discrete Algorithms, 2000 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kim, Sung-Ryul, Park, Kunsoo
openaire +2 more sources