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Prime Editing: A New Way for Genome Editing
Trends in Cell Biology, 2020Precise and efficient use of genome editing tools are hampered by the introduction of DNA double-strand breaks, donor DNA templates, or homology-directed repair. A recent study expands the genome editing toolbox with the introduction of prime editing, which overcomes previous challenges and introduces insertions, deletions, and all putative 12 types of
Hensel, Goetz +2 more
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IEEE Multimedia, 2003
This article outlines a paradigm shift in media production: the advent of computational media production that will automate the capture, editing, and reuse of video content. By integrating metadata creation and (re)use throughout the media production process, we enable the mass customization of video.
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This article outlines a paradigm shift in media production: the advent of computational media production that will automate the capture, editing, and reuse of video content. By integrating metadata creation and (re)use throughout the media production process, we enable the mass customization of video.
openaire +1 more source
To edit or not to edit: regulation of
Hundreds to millions of adenosine (A)‐to‐inosine (I) modifications are present in eukaryotic transcriptomes and play an essential role in the creation of proteomic and phenotypic diversity. As adenosine and inosine have different base‐pairing properties, the functional consequences of these modifications or ‘edits’ include altering coding potential ...
Sarah N, Deffit, Heather A, Hundley
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2013
The Cluster Editing problem asks to transform a graph into a disjoint union of cliques using a minimum number of edge modifications. Although the problem has been proven NP-complete several times, it has nevertheless attracted much research both from the theoretical and the applied side.
Sebastian Böcker, Jan Baumbach
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The Cluster Editing problem asks to transform a graph into a disjoint union of cliques using a minimum number of edge modifications. Although the problem has been proven NP-complete several times, it has nevertheless attracted much research both from the theoretical and the applied side.
Sebastian Böcker, Jan Baumbach
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Angewandte Chemie International Edition, 2023
AbstractStereochemical editing has recently risen to prominence, allowing the direct editing of organic molecules with stereocenter(s) to adjust their relative stereochemistry at a late‐stage. Several seminal light‐driven stereochemical editing reactions such as deracemization and epimerization have been successively developed.
Guangying Tan, Frank Glorius
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AbstractStereochemical editing has recently risen to prominence, allowing the direct editing of organic molecules with stereocenter(s) to adjust their relative stereochemistry at a late‐stage. Several seminal light‐driven stereochemical editing reactions such as deracemization and epimerization have been successively developed.
Guangying Tan, Frank Glorius
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Annual Review of Neuroscience, 1996
RNA editing is a term describing a variety of novel mechanisms for the modification of nucleotide sequences of RNA transcripts in different organisms. These editing events include (a) the U-insertion and -deletion type of editing found in the mitochondrion of kinetoplastid protozoa, (b) the C-insertion editing found in the mitochondrion of Physarum ...
L, Simpson, R B, Emeson
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RNA editing is a term describing a variety of novel mechanisms for the modification of nucleotide sequences of RNA transcripts in different organisms. These editing events include (a) the U-insertion and -deletion type of editing found in the mitochondrion of kinetoplastid protozoa, (b) the C-insertion editing found in the mitochondrion of Physarum ...
L, Simpson, R B, Emeson
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Current knowledge of base editing and prime editing
Molekulârnaâ biologiâModern genetic engineering technologies, such as base editing (BE) and prime editing (PE), have proven to be effective and reliable genome editing tools that do not require the introduction of double-strand breaks in DNA and the presence of donor templates.
O A, Averina +3 more
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