Results 101 to 110 of about 7,387 (242)

Los retos actuales de la salud mental desde la Salud Pública y la Administración Sanitaria. Informe SESPAS 2020

Gaceta Sanitaria, 2020
Javier Mar, María del Mar García-Calvente, Juan Cabasés, Vanessa Puig-Barrachina, Jordi Alonso   +4 more
doaj   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

To the Editor:

The Breast Journal, 2000
openaire   +7 more sources

Resgate da origem, importância e representatividade de Infarma-Ciências Farmacêuticas para a pesquisa na área farmacêutica

Infarma: Pharmaceutical Sciences, 2017
Anselmo Gomes de OLIVEIRA, Dâmaris SILVEIRA   +1 more
doaj   +1 more source

Continuam roubando nosso “ouro” Alerta: resultados de pesquisas científicas estão sendo publicados em outros países

Revista Brasileira de Agroecologia, 2012
O Brasil-Colônia historicamente já nos fez perder riquezas gigantescas aos países que nos “descobriram”. Levaram nosso ouro, nossa borracha, nossas florestas, entre tantas outras divisas que, se aqui tivessem permanecido, nos colocariam em um cenário ...
Márcio Zeppelini
doaj  

Discovery and Engineering of a Rat Endogenous Retrovirus Reverse Transcriptase for Efficient Prime Editing

Advanced Science, EarlyView.
We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma, Pengcheng Yao, Shengqi Wu, Yuanyuan Shi, Lang Qin, Baitao Li, Jiayi Zhu, Minhua Huang, Yichong Zhu, Yuwen Song, Jinhuan Pang, Ziping Guo, Guochuan Wu, Chen Wang, Kewei Xu, Ruihua Huang, Quan Kuang, Liang Qu, Changtian Pan, Xianrong Xie, Qinlong Zhu, Jiaying Huang, Qiupeng Lin   +22 more
wiley   +1 more source

DOSSIER: Intelectuales y Editores

Revista del Museo de Antropologia, 2008
El intelectual abre ideas, el editor las cierra. El escritor produce textos, el editor impresos. El intelectual escribe pero es el editor quien publica. No por nada, afirman algunos psicólogos, el pensamiento culmina con su publicación.
Gustavo Sorá
doaj  

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

Advanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee, Jumi Kim, Taehan Yoon, So Hyun Kwon, Su Chan Park, Dohyun Chun, Dohyeong Kim, Eun Jung Park, Hyunwoo Kim, Ji Min Lee   +9 more
wiley   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Expanding the Epidemiologia e Serviços de Saúde associate editor's team: strengthening editorial diversity. [PDF]

Epidemiol Serv Saude
Galvão TF, Martins MAP, Silva END, Barreto JOM.   +3 more
europepmc   +1 more source