Results 101 to 110 of about 1,249,346 (252)

Mitochondrial Quality Control in Degenerative Musculoskeletal Diseases: Signaling Networks and Therapeutic Landscapes

Advanced Science, EarlyView.
Mitochondrial quality control (MQC) collapse redefines osteoarthritis, intervertebral disc degeneration, and osteoporosis as disorders of organelle dysfunction. Damaged mitochondria leak mtDNA and metabolites, driving cGAS‐STING inflammation, epigenetic reprogramming, and metabolic memory.
Haiyang Gao, Zhangrong Cheng, Xianglong Chen, Wenbo Wu, Wang Wu, Zimu Yu, Cao Yang, Yukun Zhang   +7 more
wiley   +1 more source

Infección por coronavirus (COVID-19) en Anales de Pediatría

Anales de Pediatría, 2020
Corsino Rey Galán, Laia Alsina Manrique de Lara, Montserrat Antón Gamero, Alfredo Cano Garcinuño, Gonzalo Solís Sánchez   +4 more
doaj   +1 more source

Editorial.

AI Mag., 2002
Robot rescue and the introduction of the new AI in the News column.
openaire   +2 more sources

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

A Multi‐Structural Radiomic Digital Phenotyping Framework for Deciphering Preclinical Evolution of Degenerative Meniscal Tears

Advanced Science, EarlyView.
Subclinical matrix disruption precedes degenerative meniscal tears across the knee joint. A spatial compartmental radiomics model utilizing 3D‐DESS MRI captures early osteochondral destabilization, accurately predicting incident tears up to four years pre‐collapse. Feature attributions uncover coordinated chondral and osseous alterations, advancing non‐
Shengfa Li, Hao Liu, Yanbin Zhu, Hang Zhang, Qifeng Tao, Wenbo Zhao, Xin Miao, Shanshan Yang, Tianyu Chen, David Hunter, Changhai Ding, Ting Wang, Juan Wang, Wei Chen   +13 more
wiley   +1 more source

Rational Expectations and Market Timing: An Event Study of the China–United States Phase One Trade Deal

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Rational actors constantly incorporate information into their decision‐making behavior. Since there is often a time lag between the announcement of a policy and its implementation, an important question arises: when do rational actors incorporate new information into their market behavior, at the announcement or at the implementation of a ...
Tim Ölkers, Oliver Mußhoff
wiley   +1 more source

Editorial

Strategies in Trauma and Limb Reconstruction, 2014
openaire   +5 more sources

The First Piece of the Pattern

Patterns, 2020
Sarah Callaghan, Tessa Darbyshire
doaj   +1 more source

Editorial Editorial

Anais Brasileiros de Dermatologia, 2004
Bernardo Gontijo, Sílvio Alencar Marques, Evérton Siviero do Vale   +2 more
  +7 more sources

Patterns of Radiologic Service Utilization and Imaging Expenditure in Supercentenarians in Colombia

AGING MEDICINE, EarlyView.
Analysis of Colombian administrative health data from 2014 to 2023 identified a distinct pattern of radiologic service utilization among supercentenarians (≥ 110 years). General radiology, ultrasound, and computed tomography were the most frequently used modalities, accounting for most imaging examinations.
Gabriela Puentes, Oscar Espinosa, Valeria Bejarano, Angela Guarnizo   +3 more
wiley   +1 more source