Results 21 to 30 of about 309,481 (265)
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman +9 more
wiley +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
Editorial design and community press: redesign of a local newspaper in Curitiba
This paper reports on the redesign of Cidade Notícias, a community newspaper published in Curitiba. First, it presents background data about content and general features regarding the visual layout of the newspaper.
Eunice Liu +3 more
doaj +1 more source
Editorial Design Based on User Experience Design
This research deals with editorial design based on user experience design. The traditional editorial design has had to adapt to the new digital media composition, where multimedia audiovisual elements unthinkable a few years ago need to be integrated. The participation of the reader, as an external observer who only receives information through texts ...
Carlos Borja-Galeas +8 more
openaire +2 more sources
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Design thinking no contexto do projeto editorial: contribuições instrumentais
O projeto de livros, revistas e outros produtos editoriais se inicia a partir de um conceito que deve levar em conta o público-alvo, suas preferências, necessidades e restrições, além de apresentar um design adequado ao leitor, às editoras e ao mercado ...
Maíra Woloszyn +3 more
doaj +1 more source
Editorial: Designing for Transitions [PDF]
This is an Open Access Conference Paper. It is published by Design Research Society under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) licence. Full details of this licence are available at: http://creativecommons.org/licenses/by-nc-sa/4.0/
Joanna Boehnert +2 more
openaire +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Applying citizen science method for odor measurement in urban areas
Urban site analysis includes tangible factors such as the physical site features and intangible factors as the sensory site features like odors affect the inhabited area in the site.
Yasmine Amkieh +2 more
doaj +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source

