Results 101 to 110 of about 1,300,680 (334)

Editorial I [PDF]

, 2002
Ronnie Glavin, Nicola Maran
openalex   +1 more source

Editorial RES 2/2021 [PDF]

, 2021
Florin George Călian
openalex   +1 more source

Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity

Advanced Science, EarlyView.
Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini, Taylor V. Brysgel, Ryan J. Rahman, Eno‐Obong Essien, Saw Y. Nwe, Jichuan Wu, Aparajeeta Majumder, Manthan N. Patel, Sachchidanand Tiwari, Carolann L. Espy, Fengyi Dong, Sabrina A. Santos‐De León, Anit Shah, Vladimir V. Shuvaev, Elizabeth D. Hood, Liam S. Chase, Drew Weissman, Jeremy B. Katzen, David B. Frank, Mariko L. Bennett, Oscar A. Marcos‐Contreras, Jacob W. Myerson, Vladimir R. Muzykantov, Sahily Reyes‐Esteves, Jacob S. Brenner   +24 more
wiley   +1 more source

A genre-based study of biomedical editorials and letters to the editor: a contrastive analysis [PDF]

Ibérica, 2005
This paper reports on a genre-based contrastive analysis of the textual organization of biomedical texts. In order to provide the maximum educational value to our research, our corpus is made up of 100 biomedical texts divided as follows: 25 Letters to ...
Esther Vázquez y del Árbol
doaj  

Volume 10, Number 6 – March 1930 [PDF]

, 1930
Volume 10, Number 6 – March 1930. 42 pages including covers and advertisements. Lillie, Edward C., On the Prairie Hickey, Carroll, Little Galahads (verse) Carlson, Edward C., Zeb, the Aesthete Schneider, Francis C., His Brother\u27s Inspiration

core   +1 more source

Guest Editorial: Advanced Technologies and Services for Multimedia Big Data Processing [PDF]

, 2015
Young‐Sik Jeong, Mei‐Ling Shyu, Guandong Xu, Roland Wagner   +3 more
openalex   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

Serial, Repeated, or Single Measurements of Natriuretic Peptides (BNP or NT‐proBNP) in Estimating Cardiovascular Risk: Is It the “Importance of Change Over Time” or “The Past Is Good, But the Present Is Better,” or Both, in Clinical Context?

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Wayne L. Miller
doaj   +1 more source

Editorial: What is this cleavage of mitral valve – Commissure, indentation, cleft, or cleft-like indentation? [PDF]

, 2015
Masaki Nii
openalex   +1 more source

Structure‐Guided Engineering of a Cas12i Nuclease Unlocks Near‐PAMless Genome Editing

Advanced Science, EarlyView.
CRISPR‐Cas nucleases are limited by PAM requirements, restricting genome accessibility. Structure‐guided engineering of the compact Cas12i nuclease SF01 produced three variants with near‐PAMless, enabling efficient editing at diverse 5'‐NNTN‐3' sites. These nucleases expand the editable portion of the human genome more than fourfold, enabling efficient
Qitong Chen, Hanlin Gou, Chao Xu, Sihan Wang, Huitao Zhang, Minglei Song, Mengge Wang, Xingkun Ji, Xiaofei Wei, Yuanyan Tan, Hehua Quan, Pengyu Luo, Hanyu Shou, Pengpeng Liu, Yafeng Liang, Jian‐Kang Zhu   +15 more
wiley   +1 more source