Results 151 to 160 of about 902,007 (283)

A Conversation with Librarian-Editors

open access: yes, 2015
In brief: Ellie Collier interviews several librarian-editors about the publishing process, with a focus on “call for chapters” style books. Introduction: I began working on In the Library with the Lead Pipe in 2008 as a founding editor and author ...
Ellie Collier
core  

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Platelets – A fine balance

open access: yesPlatelets, 2017
Paul Harrison, Steve Watson
doaj   +1 more source

Best of Maine 2011, with readers\u27 and editors\u27 recommendations for the best pl

open access: yes, 2011
Best of Maine 2011, with readers\u27 and editors\u27 recommendations for the best places to go, eat and shop in ...
Editors, of Down East
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Platelets—Joining the 400 club

open access: yesPlatelets, 2018
Paul Harrison, Steve Watson
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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