Results 121 to 130 of about 21,053 (285)

Characterizing Apixaban Pharmacokinetics Through Physiologically‐Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
ABSTRACT Apixaban, a factor Xa inhibitor, is a direct oral anticoagulant with a well‐balanced elimination; it is eliminated evenly via feces, urine (with no active secretion), and as metabolites after oral administration. The common understanding is that biliary secretion and enterohepatic circulation (EHC) of apixaban are limited in humans, and that ...
Toshiaki Tsuchitani   +3 more
wiley   +1 more source

Antiphospholipid Syndrome Mimicking Acute Exacerbation of Interstitial Pneumonia: A Case Report and Literature Review

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
Acute exacerbation of interstitial pneumonia (IP‐AE) is a type of severe respiratory failure that occurs in patients with chronic interstitial pneumonia. However, a few cases of lung involvement caused by antiphospholipid antibody syndrome (APS) appearing similar to IP‐AE have been reported.
Saki Ishii   +11 more
wiley   +1 more source

New Oral Anticoagulants for Atrial Fibrillation [PDF]

open access: yes, 2017
Atrial fibrillation (AF) is the most common cardiac arrhythmia in the world. Four new oral anticoagulants have become available as alternatives for warfarin in patients with AF.
Yakobus, Y. (Yuliana)
core   +2 more sources

Evaluation of Two High‐Power Ablation Approaches in the Management of Typical Atrial Flutter: A Retrospective Study

open access: yesAnnals of Noninvasive Electrocardiology, Volume 31, Issue 1, January 2026.
To compare the acute and long‐term outcomes of high‐power ablation for typical atrial flutter using a 4‐mm irrigated catheter (4‐IC) versus an 8‐mm non‐irrigated catheter (8‐NIC). We conducted a retrospective cohort study of 215 patients who underwent cavotricuspid isthmus (CTI) ablation between January 2019 and December 2024.
Hina Pervaiz   +5 more
wiley   +1 more source

Anticoagulated patient’s perception of their illness, their beliefs about the anticoagulant therapy prescribed and the relationship with adherence: impact of novel oral anticoagulant therapy – study protocol for The Switching Study: a prospective cohort study [PDF]

open access: yes, 2016
Background Anticoagulant therapy is prescribed for millions of patients worldwide for the prevention and treatment of both arterial and venous thrombosis. Historically, only vitamin K antagonists have been available for clinicians to prescribe.
Alison Brown   +8 more
core   +2 more sources

Stability of Medications Administered via Enteral Feeding Tubes: A Systematic Review

open access: yesClinical and Translational Science, Volume 19, Issue 1, January 2026.
The graphical abstract for the stability of medicatioins administred via enteral feeding tube: A systematic review ((PROSPERO, registration number: CRD42024580820)). ABSTRACT Feeding tubes are essential for patients unable to maintain adequate oral intake, serving multiple purposes including nutrition delivery and medication administration.
Lena Alodat   +3 more
wiley   +1 more source

Efficacy and Safety of Edoxaban in Elderly Patients With Atrial Fibrillation in the ENGAGE AF–TIMI 48 Trial

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundElderly patients with atrial fibrillation are at higher risk of both ischemic and bleeding events compared to younger patients. In a prespecified analysis from the ENGAGE AF‐TIMI 48 trial, we evaluate clinical outcomes with edoxaban versus ...
Eri Toda Kato   +13 more
doaj   +1 more source

Risk factors of ischemic stroke and subsequent outcome in hemodialysis patients [PDF]

open access: yes, 2015
Background and purpose: End stage renal disease (ESRD) requiring hemodialysis (HD) carries up to a 10-fold greater risk of stroke than normal renal function. Knowledge concerning risk factors and management strategies derived from the general population
Dawson, Jesse   +9 more
core   +1 more source

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