Results 271 to 280 of about 2,259,836 (375)

Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
This study uncovered sex‐specific metabolic and lipidomic signatures of prediabetes. In PREVADIAB2 (n = 953), clustering by insulin traits revealed four phenotypes. Lipidomics showed women enriched in dihydroceramides and sphingomyelins, while men displayed a higher ceramide/sphingomyelin ratio. These sex‐metabolic phenotypes expose distinct lipidomes,
Ana F. Pina   +8 more
wiley   +1 more source

Assessing the interaction of the UCP system and fatty acids on epicardial adipose tissue mitochondrial respiration

open access: yesEuropean Journal of Clinical Investigation, EarlyView.
Epicardial adipose tissue (EAT) demonstrates higher mitochondrial activity than subcutaneous fat (SAT), particularly in NADH‐ and FAO‐linked oxidative phosphorylation (OXPHOS). While EAT expresses more UCP1, its inhibition by GDP minimally affects respiration, especially in FAO pathways, suggesting UCP1‐independence. Diabetes mellitus (DM) and coronary
Diana Santos   +12 more
wiley   +1 more source

Instrumento para Avaliação Formativa em Estágio Supervisionado de Enfermagem®: elaboration and validity. [PDF]

open access: yesRev Bras Enferm
Ramos TK   +7 more
europepmc   +1 more source

Solving the trophic puzzle: Host–parasite associations in Neotropical fig wasps associated with fig trees of section Americanae

open access: yesEcological Entomology, EarlyView.
We determined the trophic associations among fig wasp species associated with Ficus citrifolia by integrating gall morphology, the temporal sequence of wasp colonization, and oviposition behaviour. Dissection of galls produced by four gall‐inducing species at a late developmental phase enabled direct identification of occupants and inference of host ...
Leví Oliveira Barros   +2 more
wiley   +1 more source

Brazilian National Curricular Guidelines for Undergraduate Nursing: ABEn in defense of education and SUS as public goods. [PDF]

open access: yesRev Bras Enferm
Rozendo CA   +6 more
europepmc   +1 more source

Motives and predictors of modified Atkins diet discontinuation as treatment of adults with drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to explore the motives and predictors of modified Atkins diet (MAD) discontinuation as a treatment of adults with drug‐resistant epilepsy (DRE). Methods A single‐center observational longitudinal study was made of a cohort of patients treated with MAD during the first 6 years at a multidisciplinary ...
Raquel Samões   +6 more
wiley   +1 more source

Aquaporin‐1, aquaporin‐3 and aquaporin‐5 differentially modulate cell biophysical and biomechanical properties, impacting cell stiffness and cell–cell adhesion

open access: yesThe FEBS Journal, EarlyView.
GA text Overexpression of aquaporins AQP1, AQP3, or AQP5 in HEK‐293 T cells induced changes in cell biophysical properties and migration. Atomic force microscopy (AFM)–based force spectroscopy studies demonstrated that AQP1 overexpression increased cell stiffness and cell–cell adhesion, AQP3 augmented cell stiffness but reduced cell–cell adhesion ...
Catarina Pimpão   +5 more
wiley   +1 more source

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