Results 11 to 20 of about 49,055 (151)

Potential biomarkers for fatal outcome prognosis in a cohort of hospitalized COVID‐19 patients with pre‐existing comorbidities

open access: yesClinical and Translational Science, Volume 16, Issue 12, Page 2687-2699, December 2023., 2023
Abstract The difficulty in predicting fatal outcomes in patients with coronavirus disease 2019 (COVID‐19) impacts the general morbidity and mortality due to severe acute respiratory syndrome‐coronavirus 2 infection, as it wears out the hospital services that care for these patients.
Ruth Lizzeth Madera‐Sandoval   +29 more
wiley   +1 more source

The Four Pillars for Successful Regenerative Therapy in Endodontics: Stem Cells, Biomaterials, Growth Factors, and Their Synergistic Interactions

open access: yesStem Cells International, Volume 2022, Issue 1, 2022., 2022
Endodontics has made significant progress in regenerative approaches in recent years, thanks to advances in biologically based procedures or regenerative endodontic therapy (RET). In recent years, our profession has witnessed a clear conceptual shift in this therapy.
C. Brizuela   +5 more
wiley   +1 more source

Crosstalk between Body Microbiota and the Regulation of Immunity

open access: yesJournal of Immunology Research, Volume 2022, Issue 1, 2022., 2022
The microbiome corresponds to the genetic component of microorganisms (archaea, bacteria, phages, viruses, fungi, and protozoa) that coexist with an individual. During the last two decades, research on this topic has become massive demonstrating that in both homeostasis and disease, the microbiome plays an important role, and in some cases, a decisive ...
Carolina Rojas   +8 more
wiley   +1 more source

Sublingual dermoid cyst in an infant: A case report and review of the literature

open access: yesClinical Case Reports, Volume 8, Issue 8, Page 1403-1408, August 2020., 2020
Dermoid cysts usually occur later in the second decade of life; we present the approach of an unusual case of an infant who presented a cyst within the oral cavity, which is important because it can be confused with other pathologies. Abstract Dermoid cysts usually occur later in the second decade of life; we present the approach of an unusual case of ...
Madeleine Edith Vélez‐Cruz   +7 more
wiley   +1 more source

Chitosan‐Based Delivery of Avian Reovirus Fusogenic Protein p10 Gene: In Vitro and In Vivo Studies towards a New Vaccine against Melanoma

open access: yesBioMed Research International, Volume 2020, Issue 1, 2020., 2020
Reovirus is known to have an anticancer effect in both the preclinical and clinical assays. Current evidence suggests that the reovirus‐mediated impact on tumor growth depends on the activation of specific antitumor immune responses. A feasible explanation for the oncolytic effects and immune system activation is through the expression of the fusogenic
Claudia Robles-Planells   +16 more
wiley   +1 more source

Chitosan‐Based Nanoparticles for Intracellular Delivery of ISAV Fusion Protein cDNA into Melanoma Cells: A Path to Develop Oncolytic Anticancer Therapies

open access: yesMediators of Inflammation, Volume 2020, Issue 1, 2020., 2020
Oncolytic virus therapy has been tested against cancer in preclinical models and clinical assays. Current evidence shows that viruses induce cytopathic effects associated with fusogenic protein‐mediated syncytium formation and immunogenic cell death of eukaryotic cells.
Claudia Robles-Planells   +15 more
wiley   +1 more source

Genome Damage in Rats after Transplacental Exposure to Jatropha dioica Root Extract

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2019, Issue 1, 2019., 2019
Jatropha dioica is traditionally used owing to its antiviral, antifungal, and antimicrobial properties. But, toxicological information regarding J. dioica root total extract is currently limited. The aim of this work was to evaluate in a rat model, the transplacental genotoxicity effect of J. dioica aqueous root total extract. Three different J. dioica
Gabriela Morales-Velazquez   +9 more
wiley   +1 more source

Mathematical Modeling for Pharmaco‐Kinetic and ‐Dynamic Predictions from Controlled Drug Release NanoSystems: A Comparative Parametric Study

open access: yesScientifica, Volume 2019, Issue 1, 2019., 2019
Predicting pharmacokinetics, based on the theory of dynamic systems, for an administered drug (whether intravenously, orally, intramuscularly, etc.), is an industrial and clinical challenge. Often, mathematical modeling of pharmacokinetics is preformed using only a measured concentration time profile of a drug administered in plasma and/or in blood ...
Grigorios P. Panotopoulos   +2 more
wiley   +1 more source

Evaluation of the Coating with TiO2 Nanoparticles as an Option for the Improvement of the Characteristics of NiTi Archwires: Histopathological, Cytotoxic, and Genotoxic Evidence

open access: yesJournal of Nanomaterials, Volume 2018, Issue 1, 2018., 2018
For the EPD, different voltages and different times were used. Male rats were used in four groups (n = 3) with different treatments. The blood sample was obtained for genotoxic analysis and liver and kidney organs were removed for histopathological analysis.
Javier Morán-Martínez   +10 more
wiley   +1 more source

Predicting Facial Biotypes Using Continuous Bayesian Network Classifiers

open access: yesComplexity, Volume 2018, Issue 1, 2018., 2018
Bayesian networks are useful machine learning techniques that are able to combine quantitative modeling, through probability theory, with qualitative modeling, through graph theory for visualization. We apply Bayesian network classifiers to the facial biotype classification problem, an important stage during orthodontic treatment planning. For this, we
Gonzalo A. Ruz   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy