Results 51 to 60 of about 1,027,677 (183)

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, Volume 38, Issue 2, 8 January 2026.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Enseñanza-aprendizaje por indagación de los contenidos relativos a la salud en el grado de educación primaria [PDF]

, 2013
En este trabajo se quiere poner de manifiesto la importancia que conlleva una adecuada formación del futuro profesor de educación primaria en los contenidos del ámbito de la salud.
Charro Huerga, Elena, Charro Huerga, Esther, Gómez Niño, Ángela   +2 more
core   +1 more source

Comprehensive profiling of Aβ40 and Aβ42 fibril‐interacting proteins reveals PRKCG as a drug‐targetable regulator of amyloidogenesis in Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Proteins interacting with amyloid beta (Aβ) fibrils could be key to plaque formation in Alzheimer's disease (AD) and represent potential biomarkers and therapeutic targets. Previous proteomic studies using microdissected plaques might have captured non‐specific components rather than true Aβ interactors.
Ana Montero‐Calle, Raquel Coronel, Juliana Manosalva, Diego Megías, Vivian de los Ríos, Alberto Rábano, Alberto Peláez‐García, Javier Martínez‐Useros, María Jesús Fernández‐Aceñero, Isabel Liste, Rodrigo Barderas   +10 more
wiley   +1 more source

Health education strategies for older people: experiences and challenges [PDF]

, 2015
Esta é uma revisão integrativa que tem como objetivo avaliar a produção científica relacionada à educação em saúde para idosos no Brasil, entre 2007 a 2013.
Filipe, Elvira Maria Ventura, Mendonça, Francielle Toniolo Nicodemos Furtado de, Santos, Álvaro da Silva, Silveira, Rodrigo Eurípedes da   +3 more
core   +1 more source

Synthesis of Benzopyrans and Quinolines with Nitrogenated Chain and Their Cytotoxicity Against Human Cancer Cell Lines

ChemMedChem, Volume 21, Issue 2, January 2026.
Natural products and/or their structural analogs represent the greatest number of approved small‐molecules as antitumor agents. We report the synthesis of 2‐propanamide and 2‐propanamine dihydrobenzopyrans and 2‐ and 2,3‐disubstituted quinolines to evaluate their cytotoxicity against human A549 (lung), A2058 (melanoma), HepG2 (liver), MCF‐7 (breast ...
Bernabeu‐Sanchis Álvaro, Thomas A. Mackenzie, Maria C. Ramos, Ainhoa García, Carlos Villarroel‐Vicente, Laura Vila, José R. Tormo, Diego Cortes, Nuria Cabedo   +8 more
wiley   +1 more source

Determinantes sociales de la salud en Andalucía [PDF]

, 2017
Este trabajo es el fruto del proyecto IMPACT-A financiado por el Centro de Estudios Andaluces en su convocatoria de ayudas a proyectos de investigación 2014.
Álvarez Gálvez, Javier
core   +1 more source

Gut Microbiota Composition in Adolescents From Mexico City, Associations With Nutritional and Socioeconomic Factors: Results From a Pilot Study

Molecular Nutrition &Food Research, Volume 70, Issue 2, 29 January 2026.
This study analyzed the gut microbiota composition of 95 adolescents and its relationship with body mass index, dietary habits, and socioeconomic status using 16S rRNA sequencing (V3‐V4). The dominant phyla in the gut microbiome were Bacteroidetes, Firmicutes, and Proteobacteria, while enterotype‐like patterns were mainly driven by Bacteroides and ...
Armando Navarro, Gerardo E. Rodea, Aldo Hugo de la Cruz‐Montoya, Clara Estela Díaz‐Velásquez, Felipe Vaca‐Paniagua, Armando Navarro‐Cid del Prado, Laura L. Tirado‐Gómez, Ariel Vilchis‐Reyes, Guadalupe García de la Torre, Verónica Cruz‐Licea, Carlos Eslava‐Campos, Hugo G. Castelán‐Sánchez   +11 more
wiley   +1 more source

Hepatitis C genotipo viral 5 en México: reporte de caso con tratamiento exitoso y revisión de la literatura

Revista de Gastroenterología de México, 2013
El genotipo 5 del virus de la hepatitis C (VHC) es sumamente raro; además, existe poca literatura respecto a su tratamiento. Presentamos el caso de un paciente con VHC genotipo 5, que presumiblemente adquirió la enfermedad por medio de transfusión ...
M.A. Rubio-Lezama, R. López-Alférez, L. Santillán-Arreygue, M. Romero-Figueroa   +3 more
doaj   +1 more source

Efectividad del modelo etapas de cambio en los conocimientos, actitudes y practicas en salud oral en los alumnos de septimo basico de un establecimiento educacional municipalizado de Talca, 2009 [PDF]

, 2009
102 p.INTRODUCCIÓN: Se ha venido afrontando en los adolescentes la problemática de la falta de interés que muestran hacia la atención estomatológica, que se demuestra por la dificultad para lograr que asistan a los servicios dentales, finalicen los ...
Núñez Franz, María Loreto (Prof. Guía), Valdes Kanelos, Tania Solange   +1 more
core  

Thermal noise lowers the accuracy of rotationally invariant harmonics of diffusion MRI data and their robustness to experimental variations

Magnetic Resonance in Medicine, Volume 95, Issue 1, Page 204-219, January 2026.
Abstract Purpose Rotational invariants (RIs) are at the root of many dMRI applications. Among others, they are presented as a sensible way of reducing the dimensionality of biophysical models. While thermal noise impact on diffusion metrics has been well studied, little is known on its effect on spherical harmonics‐based RI (RISH) features and derived ...
Guillem París, Tomasz Pieciak, Derek K. Jones, Santiago Aja‐Fernández, Antonio Tristán‐Vega, Jelle Veraart   +5 more
wiley   +1 more source