Results 121 to 130 of about 21,060,376 (300)
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
This paper describes the potential of carbon dot nanocomposites (CDs) synthesized from waste materials by top-down and bottom-up state-of-the-art approaches.
S. Varadharajan +4 more
doaj +1 more source
Newfire\u27s Higher Education Partner Program [PDF]
This paper announces the Newfire Higher Education Partners Program.
Desmarais, Norman
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Editorial Team Tuning Journal for Higher Education
doaj +4 more sources
Preparing Special Education Higher Education Faculty
L. Debettencourt +3 more
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Este artigo tem por objetivo descrever a trajetória do ensino de graduação desenvolvido na Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo (EERP-USP), ao longo dos seus 50 anos (1953-2003), trazendo subsídios para reflexões acerca do ...
Maria José Clapis +5 more
doaj
Gamificacion in education and active methodologies at Higher education [PDF]
In recent years, there has been an increasing interest in applying Gamification in Education, which can be defined as the application of game design elements to learning activities.
Bentabol-Manzanares, Maria Amparo +8 more
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

