Results 71 to 80 of about 968,992 (277)

Exploring assessment of medical students\u27 competencies in pain medicine - A review [PDF]

, 2019
Introduction: Considering the continuing high prevalence and public health burden of pain, it is critical that medical students are equipped with competencies in the field of pain medicine. Robust assessment of student expertise is integral for effective
Adillon, Adwan, Al-Rukban, Ali, Ali, Ameringer, Anderson, Antman, Argyra, Arwood, Banja, Biggs, Breivik, Briggs, Briggs, Carr, Carraccio, Case, Cohen, Corrigan, Dominick, Downing, Driessen, Eijsvogels, Emke, Epstein, Epstein, Erickson, Fabbian, Ferris, Fete, Finnerup, Fishman, Fishman, Frank, Frenk, Gatchel, Gehlhar, Ger, Gerbershagen, Gordon, Green, Gruppen, Hanna, Haq, Harden, Harendza, Harlen, Hirsh, Hoy, Hunter, Hunter, Kaki, Kennedy, Khan, Lasch, Lee, Leila, Lockyer, Loeser, Manalo, Manchikanti, Merrill, Mezei, Miller, Morley-Forster, Morris, Murinson, Nabishah, Niemi-Murola, Nimmaanrat, Oudkerk Pool, Paneduro, Pilowsky, Plymale, Portenoy, Puljak, Pöyhiä, Rainville, Reeves, Salam, Schopflocher, Schreiner, Schuwirth, Shipton, Shipton, Siddall, Silva, Sloan, Sloan, Sloan, Stevens, Strohbuecker, Symonds, Tauben, Tellier, Terry, Thomson, Turner, Twigg, van den Beuken-van Everdingen, van der Vleuten, Wass, Watt-Watson, Watt-Watson, Weiner, Weinstein, Weissman, Wijnen-Meijer, Yanni   +109 more
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Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

THE ROLE OF FACTORS AFFECTING THE FORMATION OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION

Рациональная фармакотерапия в кардиологии, 2017
Aim. To study the combination and contribution of risk factors (age, hypertension (HT), obesity, diabetes mellitus, chronic kidney disease (CKD), length of illness) leading to the formation of chronic heart failure (CHF) with preserved ejection fraction (
M. V. Kurkina, A. G. Avtandilov, I. A. Krutovcev   +2 more
doaj   +1 more source

Evaluating the effectiveness of the Emergency Neurological Life Support educational framework in low-income countries. [PDF]

, 2018
BackgroundThe Emergency Neurological Life Support (ENLS) is an educational initiative designed to improve the acute management of neurological injuries. However, the applicability of the course in low-income countries in unknown.
Acharya, Subhash, Bellini, Antonio, Goffi, Alberto, Hemphill, J Claude, McCredie, Victoria A, Shrestha, Gentle S, Singh, Jeffrey M   +6 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Refractory gastro-oesophageal reflux disease : a major management issue in clinical practice [PDF]

, 2009
CITATION: Van Rensburg, C. 2009. Refractory gastro-oesophageal reflux disease : a major management issue in clinical practice. Continuing Medical Education, 27(5):210-214.The original publication is available at http://www.cmej.org.zahttp://www.cmej.org ...
Van Rensburg, Christo
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The role of primary healthcare professionals in oral cancer prevention and detection [PDF]

, 2003
AIM: To investigate current knowledge, examination habits and preventive practices of primary healthcare professionals in Scotland, with respect to oral cancer, and to determine any relevant training needs. SETTING: Primary care.
A Mashberg, C Scully, C Scully, CE Dawson, CG Cowan, D Soutar, GJ Macfarlane, GJ Macfarlane, H Moller, I Hindle, J Gibson, J Llewelyn, JF Schnetler, K W Stephen, L M D Macpherson, LMD Macpherson, M F McCann, MF McCann, MGJ Haughney, NW Johnson, PB Lockhart, PM Speight, PM Speight, RH Secker-Walker, V I Binnie   +24 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Continuing Medical Education (CME): A Reappraisal

Canadian Medical Education Journal, 2011
A concise commentary on continous medical education.
Khalid Al Aboud, V Ramesh
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