Results 161 to 170 of about 3,955,893 (324)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

THE ESSENCE OF EDUCATION IN SPECIALIZED EDUCATIONAL INSTITUTIONS FOR CHILDREN WITH SPECIAL EDUCATION NEEDS

, 2022
This article contains opinions about the content and essence of providing education to children with special educational needs. Also, the essence of education of specialized boarding schools is explained.
openaire   +2 more sources

AI for Accessible Education: Personalized Audio-Based Learning for Blind Students [PDF]

arXiv
Blind and visually impaired (BVI) students face significant challenges in traditional educational settings. While screen readers and braille materials offer some accessibility, they often lack interactivity and real-time adaptability to individual learning needs.
arxiv  

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

FEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui, Ariel Kushmaro, Hana Barak, Anja Poehlein, Rolf Daniel, Hans‐Jürgen Mägert   +5 more
wiley   +1 more source

An open chat with…Pierre Santucci: a testimonial on why we should engage with scientific societies and their journals

FEBS Open Bio, EarlyView.
Pierre SANTUCCI is a principal investigator at the CNRS—Aix Marseille Université and recipient of a FEBS Excellence Award. He was also recently appointed FEBS Open Bio Publishing Liaison Officer. In this Open Chat with…, he discusses the importance of engaging with scientific societies and their journals, and highlights through some of his personal ...
Pierre Santucci, Ioannis Tsagakis
wiley   +1 more source

Development of the Parent–Child Communication Quality Scale from the Perspective of Children’s Psychological Needs

Behavioral Sciences
Parent–child communication plays a crucial role in children’s healthy growth. Nevertheless, there is currently a paucity of instruments designed to measure the quality of parent–child communication from a psychological perspective.
Wenhui Lyu, Xiaohui Shi, Zhiheng Xiong, Yujie Mu   +3 more
doaj   +1 more source

The Origin of Special Education

Education Inquiry, 2011
The article analyses the forces behind the establishment and expansion of special education within the Swedish elementary school between 1842, when schooling became compulsory, and the gradual introduction of the experimental comprehensive school in the 1950s.
openaire   +3 more sources

The Long Term Effects of a 12‐Session Community Exercise Program on Health Measures in Cancer Patients

Aging and Cancer, EarlyView.
ABSTRACT Purpose To assess the long‐term effects of a community cancer exercise program on quality of life, fatigue, weight, waist circumference, physical activity levels, lower extremity strength, body mass index (BMI), heart rate, and blood pressure, across non‐metastatic and metastatic patients.
Isaac Oppong, Roozbeh Naemi
wiley   +1 more source

Development of an Inclusive Educational Platform Using Open Technologies and Machine Learning: A Case Study on Accessibility Enhancement [PDF]

arXiv
This study addresses the pressing challenge of educational inclusion for students with special needs by proposing and developing an inclusive educational platform. Integrating machine learning, natural language processing, and cross-platform interfaces, the platform features key functionalities such as speech recognition functionality to support voice ...
arxiv