Subthalamic Nucleus Oscillatory Characteristics in Meige, Cervical Dystonia and Generalized Dystonia
ABSTRACT Objective Deep brain stimulation offers a unique opportunity to record neural activity of the basal ganglia. While much work in dystonia has focused on the globus pallidus internus, expanding research to investigate subthalamic nucleus (STN) activity in various dystonia types is critical to provide a comprehensive understanding of dystonia ...
Zhu Guan‐Yu+14 more
wiley +1 more source
The extent to which family doctors have the ability to deal with patients with disabilities. [PDF]
Saffar OA.
europepmc +1 more source
Cortical Excitability Before and After Long‐Term Perampanel Treatment for Epilepsy
ABSTRACT Objective Antiseizure medications (ASMs), which may influence cortical excitability, are the mainstay of epilepsy treatment. Transcranial magnetic stimulation (TMS) helps evaluate cortical excitability. We assessed changes in TMS responses using serial TMS measurements in people treated with an adjunctive noncompetitive AMPA‐receptor ...
Robert M. Helling+6 more
wiley +1 more source
Multifactorial Analysis of Oral Health-Related Quality of Life in Children with Special Health Care Needs: A Case-Control Study. [PDF]
Fahmi MK+6 more
europepmc +1 more source
ABSTRACT Objective Sleep spindles are an electrophysiological fingerprint of the sleeping human brain. They can be described in terms of duration, frequency, amplitude, and density, and vary widely according to age and sex. Spindles play a role in sleep and wake functions and are altered in several neurological and psychiatric disorders.
Julien Coelho+8 more
wiley +1 more source
Quality evaluation of the spatial characteristics of basic public services: a case study of people with disabilities in China between 2012 and 2021. [PDF]
Yuan D, Guo J.
europepmc +1 more source
KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini+24 more
wiley +1 more source
Preschool and primary school teachers' attitude towards inclusive education for students with autism spectrum disorders in Ethiopian public schools: multicenter cross-sectional study. [PDF]
Tsegaye M+3 more
europepmc +1 more source
Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden+15 more
wiley +1 more source
Smart Accessibility and Quality of Life in Education: A Systematic Review of Adolescent Support and Universal Access. [PDF]
Alhasan NA, Lombardi M, Al-Ajmi NS.
europepmc +1 more source