Results 161 to 170 of about 6,218,601 (289)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Education needs in oxygen therapy for individuals with interstitial lung disease. [PDF]

BMJ Open Respir Res
Rowland SD, Sharpe H, Ferrara G, Johannson KA, Kalluri M, Thompson S, Stickland MK.   +6 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Contemporary perspectives and debates in student ultrasound education: exploring didactic elements and theoretical aspects. [PDF]

BMC Med Educ
Recker F, Sänger SL, Dong Y, Gschmack A, Jenssen C, Möller K, Neubauer R, Blaivas M, Prats MI, Ruppert J, Sirli R, Weimer J, Westerway SC, Zervides C, Dietrich CF.   +14 more
europepmc   +1 more source

Exploring Blended Learning Models Supported by Mobile Interactive Technologies in Higher Education

Fang Chen
openalex   +2 more sources

The contribution of systems and service research to rethinking higher education programs: a T-shaped model

, 2018
Maria Luisa Saviano, Francesco Polese, Francesco Caputo, Leonard Walletzký   +3 more
openalex   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Towards a Sustainable Future: Embedding Planetary Health in Allied Health Professional Education Through the Lens of Indigenous Knowledges. [PDF]

Health Promot J Austr
McPherson K, Barradell S, Li K, Watkins M, Phillips A.   +4 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Determinants of contraceptive use among married women in Rwanda: evidence from women's empowerment-related indicators in the 2019/2020 Demographic and Health Survey. [PDF]

BMJ Public Health
Twagirumukiza E, Munyaneza E, Bubanje V, Girimpundu R, Mvuyekure B, Sebera E.   +5 more
europepmc   +1 more source