Results 51 to 60 of about 272,670 (303)

Brexit i jego skutki dla Niemiec z perspektywy ekonomicznej i społecznej [PDF]

open access: yes, 2019
At the end of March 2017, the British government initiated the legal procedure of withdrawal from the EU, beginning the two-year countdown towards Brexit. However, as of August 2019, the final outcome of the Brexit negotiations is still pending.
Bartkowiak, Marcin, Ratajczak, Anna
core   +2 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Informal Jobs and Trade Liberalisation in Argentina [PDF]

open access: yes, 2013
Rapid trade liberalisation can exert profound effects on labour markets. Domestic firms, to sustain competitiveness for survival, could react through cutting labour benefits to achieve cost reductions.
Acosta, P., Montes-Rojas, G.
core   +3 more sources

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Experiences of Capitalism in India and Pakistan [PDF]

open access: yes, 2014
The objective of this study is to examine the economic policies and socio-economic changes which have taken place in South Asia for the last six decades.
Siddiqui, Kalim
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Developing Entrepreneurial Competencies in Coffee Farming: Strategic Approaches for Kepahiang Regency

open access: yesJurnal Agrisep
National coffee consumption by Indonesians has consistently increased over the past five years, while exports of raw coffee beans have declined. On the other hand, exports of ground coffee, coffee beverages, and instant coffee have grown, except for a ...
Timbul Rasoki, Ana Nurmalia
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

An HEI-disaggregated input-output table for Wales [PDF]

open access: yes, 2010
This paper describes how the education sector of the Welsh Input-Output tables is disaggregated to identify a separate sector for each of Wales’s twelve Higher Education Institutions (HEIs).
Hermannsson, Kristinn   +3 more
core   +1 more source

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