Results 121 to 130 of about 7,245,178 (315)

Activities of daily living mediate the association between balance and falls in middle aged and older adults

Scientific Reports
Falls constitute a significant public health issue affecting middle-aged and older adults.The consequences of falls extend beyond physical injuries and compromised quality of life to encompass psychological and socioeconomic dimensions.
Jiaran Jiang, Quan Zhou, Chuanxia Zhang, Keer Cong   +3 more
doaj   +1 more source

Establishment of Charter Schools in the Commonwealth of Virginia [PDF]

, 2016
Virginia is facing significant challenges related to public education such as decreased funding for public education, decreased teacher salaries, and overcrowded classrooms.
Epps, Shermese, Grace E. Harris Leadership Institute, Virginia Commonwealth University, Pegram, Germika, Reed, Edward, Sampe, Brenda, Warren, Courtney   +5 more
core   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

SELF-ASSESSMENT OF EDUCATIONAL ACTIVITY OF GENERAL SECONDARY EDUCATION INSTITUTION

, 2022
S. REZNIK
openalex   +2 more sources

The Armed Forces Covenant in action?: Part 4: Education of service personnel fifth report of session 2013-14 report, together with formal minutes, oral and written evidence [PDF]

, 2013
Enabling power: Education Act 1996, s. 537A (4) (5) (6). Issued: 29.05.2013. Made: 20.05.2013. Laid: 29.05.2013. Coming into force: 28.06.2013. Effect: S.I. 2009/1563 amended.
Arbuthnot, James
core  

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

INTERPRETATİON OF THE "TEACHİNG STRATEGİES BLOCK ELEMENTS" OF THE SUBJECT CURRİCULUM AT THE GENERAL EDUCATİON LEVEL BASED ON THE "SYSTEMSTRUCTURE" APPROACH

, 2023
F. İbrahimov, G. Abdullayeva, S. Amrahova   +2 more
openalex   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source