Results 51 to 60 of about 5,244,685 (296)

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Education and general culture

Revista MENDIVE, 2004
This article explains the term of integral general culture by means of an analysis of its appearance in speeches and interviews of the Commandant in Chief, Fidel Castro Ruz, and other leaders of the Revolution, as well as the interaction of education ...
Yadyra Piñera Concepción, Idalberto Rodríguez Poo   +1 more
doaj  

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Sustainability Education and Critical Thinking Integration in General Education

International Journal of Current Educational Studies
Education and critical thinking are integral in the achievement of Sustainable Development Goals (SDGs). Thus, this study aims to examine the extent of integration of sustainability education (SE) and critical thinking (CT) in General Education (GE ...
Joseph Jintalan, Rodrigo A. Litao
doaj   +1 more source

Perspectives on blended learning through the on-line platform, LabLessons, for Chemistry

Journal of Technology and Science Education, 2018
The effectiveness of blended learning was evaluated through the integration of an online chemistry platform, LabLessons. Two modules, Titration and Formation of Hydrogen, were designed by college mentors alongside classroom chemistry teachers to engage ...
Teeba Jihad, Edward Klementowicz, Patrick Gryczka, Chappel Sharrock, Macrae Maxfield, Yougjun Lee, Jin Kim Montclare   +6 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Challenges of General Practice Education in Iran: A Qualitative Study [PDF]

Strides in Development of Medical Education, 2013
Background & Objective: According to some evidences medical graduates do not evaluate their skills and capabilities to perform professional responsibilities at an acceptable level In other words there is a disagreement among authorities and experts of ...
Mohammadreza Amiresmaili, Mahmood Nekoei Moghadam, Mahmood Moosazadeh, Elaheh Pahlavan   +3 more
doaj  

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Discipline-based Art Education and the Viability of Introducing It, through General Education, in the Kingdom of Saudi Arabia [PDF]

Journal of Islamic Studies, 2004
The research is one of the very few works that deal with this theory in Arabic. This is one of the most important (if not the most important) of all theories in the realm of art education.
Mohamed Hussein A. Aldoyhi
doaj