An oligo-swapping method: preparation of mismatch repair-monitoring substrate using a nicking endonuclease. [PDF]
MethodsXTakedachi A, Hayashida M, Kuraoka I.
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Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse
Advanced Science, EarlyView.We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang +7 more
wiley +1 more source
Methodological Comments to "Comparative Effects of Two Acupuncture Protocols in the Management of Chronic Insomnia: A Randomized Controlled Trial" [Letter]. [PDF]
Nat Sci SleepZhou G, Shen P, Wan Y.
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Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source
Surname match/mismatch revisited: It may no longer matter for partner choice. [PDF]
PLoS OneNakazawa T, Shinohara N, Fukano Y.
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DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics
Advanced Science, EarlyView.This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei +12 more
wiley +1 more source
Spatial paradox between urban center expansion and vitality loss in Guangzhou, China. [PDF]
Sci RepChen Y, Zhang L, Lu X, Zhang D, Deng A.
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Advanced Science, EarlyView.We present a textile‐compatible, self‐healing liquid metal ink and a dual‐mask printing technique for high‐resolution patterning. Using this approach, we demonstrate high‐performance millimeter‐wave (mmWave) electronic textiles that exhibit exceptional insensitivity to deformation.
Lu Ju +11 more
wiley +1 more source
Trap versus trade-off: cohort evidence on overeducation, income returns, and group disparities after China's higher education expansion. [PDF]
Front SociolZhang Y, Liu Y, Yun Q, Wang J.
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Advanced Science, EarlyView.This study reports the development of a fully humanized bispecific T cell engager targeting IL13RA2, a tumor‐associated antigen enriched in glioblastoma. This off‐the‐shelf immunotherapy drives potent, antigen‐dependent T cell activation and tumor killing, and prolongs survival in experimental GBM and other solid tumors models without detectable off ...
Joseph T. Duffy +16 more
wiley +1 more source