What predicts legislative success of early care and education policies?: Applications of machine learning and Natural Language Processing in a cross-state early childhood policy analysis. [PDF]
PLoS One, 2021 Park SO, Hassairi N.
europepmc +1 more source
Institutional Variation in Enrollment of Low-Income Students: The Role of Prices, Financial Aid Policies and Selectivity [PDF]
, 2013 Socioeconomic diversity in tertiary education has come under increased scrutiny over the past few years. Policy makers and practitioners within higher education have devoted greater attention to encouraging more low-income students to pursue a college ...
Monks, James
core +1 more source
A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer
Advanced Science, EarlyView.A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang +15 more
wiley +1 more source
Scientific ReportsWhile AI-powered mental health tools have gained momentum as accessible and user-centered alternatives to traditional services, the psychological processes through which they exert influence remain insufficiently theorized.
Xiaoxiao Sun +3 more
doaj +1 more source
Tackling low educational achievement [PDF]
, 2007 This report examines the factors underlying low achievement in British education. It is important to find out why tens of thousands of young people leave school with no or very few qualifications. Low achievement at age 16 is associated with disadvantage
Cassen, Robert, Kingdon, Geeta
core
Advanced Science, EarlyView.This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang +21 more
wiley +1 more source
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression
Advanced Science, EarlyView.This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng +8 more
wiley +1 more source
The Matanuska-Susitna Borough Community Survey, 2006: A Sourcebook of Community Attitudes [PDF]
, 2006 The Matanuska-Susitna Borough Community Survey (Mat-Su Survey) was a cooperative effort on the part of Mat-Su College, the University of Alaska-Anchorage (UAA) and the Matanuska-Susitna Borough which asked Mat-Su Borough residents to evaluate the quality
Farrell, Chad, Langworthy, Robert H.
core
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
Advanced Science, EarlyView.This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
Increasing the Economic Development Benefits of Higher Education in Michigan [PDF]
This paper considers how a state such as Michigan can increase the economic development benefits of higher education. Research evidence suggests that higher education increases local economic development principally by increasing the quality of the local
Timothy J. Bartik
core +1 more source