Frontiers in MicrobiologyIntroductionSustained and sub-optimal antimicrobial use drives antimicrobial resistance (AMR), a major health systems challenge in low- and middle-income countries (LMICs) such as India.
Vinay Modgil +11 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The development of university-level distance education in the context of Hong Kong's transition from a British colony to a special administrative region of China [PDF]
China resumed sovereignty over Hong Kong on I July, 1997. After being a British colony for more than 150 years, Hong Kong became a Special Administrative Region of China following the "one country, two systems" policy.
Leung, Wing-chung
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Scaffolding in Health Sciences Education Programmes: An Integrative Review. [PDF]
Med Sci Educ, 2023 Masava B, Nyoni CN, Botma Y.
europepmc +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
An analytical understanding of how external sources inform and impact upon Somaliland’s national education and teacher education policy making processes [PDF]
, 2009 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.This thesis investigates how external sources inform and impact Somaliland’s national teacher education policy making processes. In this research, external
Ahmed, Hassan Suleiman
core +1 more source
Unravelling the impact of dental workforce training and education programmes on policy evolution: a mixed-method study protocol. [PDF]
Health Res Policy Syst, 2023 Lin GSS, Goh SM, Halil MHM.
europepmc +1 more source
The EAA educational programme [PDF]
International Journal of Andrology, 2005 openaire +2 more sources
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
The Evolution of University Access Programmes in Ireland [PDF]
The aim of this report is to explore the historical development of third level access programmes in Ireland, that is, programmes aimed at improving access to third level education by the socio-economically disadvantaged.
Patricia O’ Reilly
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