Results 101 to 110 of about 18,592,957 (353)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
An exploratory study of students’ perceptions of advice and support services in a science university
Frontiers in MedicineThis exploratory qualitative study investigates the experiences of health sciences students with academic advising in an English as a Medium of Instruction (EMI) context. Through virtual semi-structured interviews with four students, the study identifies
Abdulaziz Mohammed Althewini +1 more
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
, 2017 Entrepreneurship Education in Colleges and universities is a profound reform of China's higher education paradigm. Which is a necessary choice for Chinese universities to break through the traditional educational model.
He Jiang, Wei Xiong, Yonghui Cao
semanticscholar +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
ENHANCING EDUCATION QUALITY THROUGH INTERNAL QUALITY ASSURANCE STRATEGIES
ProfetikaThe objective of this study is to 1) assess methods for enhancing educational quality via internal quality assurance, and (2) evaluate the effects of internal quality assurance within the Muhammadiyah Middle School (SMP) of Special Program at Kottabarat,
Suyanto Suyanto, Yetty Faridatul Ulfah
doaj +1 more source
Arts for All Higher Education Think Tank [PDF]
, 2010 As we enter the 21st century -- the global information age -- we must ensure our students are equipped to thrive in an environment that will require them to be able to shift their thinking and remain open to learning throughout their lives.
core
Convexity, quality and efficiency in education [PDF]
Journal of the Operational Research Society, 2017 While Data Envelopment Analysis has many attractions as a technique for analysing the efficiency of educational organisations, such as schools and universities, care must be taken in its use whenever its assumption of convexity of the prevailing technology and associated production possibility set may not hold.
openaire +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source