Results 171 to 180 of about 18,592,957 (353)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Analyzing the Market for Shadow Education in Pakistan: Does Private Tuition Affect the Learning Gap between Private and Public Schools?

open access: yesLahore Journal of Economics
Over the past decade, Pakistan has seen the rapid growth of a third sector in education: shadow education. According to the Annual Survey of Education Report (2013), 34 percent of private school students and 17 percent of public school students ...
Bisma Haseeb Khan, Sahar Amjad Shaikh
doaj  

First Class in Learning -- First Class in Life: How Washington's Early Childhood Education Career and Wage Ladder Delivers First-Class Care [PDF]

open access: yes, 2010
High-quality early learning cannot be achieved or sustained when the bonds between teacher and child are broken because teachers leave their jobs to gain higher paid employment in order to support their own families.
Gary Burris, Hannah Lidman, John Burbank
core  

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Role of Education in Economic Growth [PDF]

open access: yes
This study examines the effect of the quantity and quality of education on economic growth. Using a number of proxy variables for the quantity and quality of education in a cross section of low and medium income countries, this study finds that education
Cooray, Arusha
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Manajemen Kaderisasi Guru Al-Qur’an untuk Meningkatkan Mutu Pendidikan di Pondok Pesantren Al-Urwatul Wutsqo Bulurejo Diwek Jombang

open access: yesAl-Idaroh: Jurnal Studi Manajemen Pendidikan Islam, 2019
This study is done in al Urwatul Wutsqo boarding school, and focusing on three aspects, such as cadres forming quality; cadres forming of al Qur’an teacher to increase education quality; and the problems occurred in conducting cadres forming in al ...
Moh. Zahiq
doaj  

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