Results 71 to 80 of about 15,152,515 (292)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
National Quality Framework snapshot Q2 2015
, 2015 This 10th report in the National Quality Framework series rates children’s education and care services across Australia. Findings include: 14 910 children’s education and care services operating under the NQF across Australia 9347 or 63 per cent of ...
Australian Children’s Education and Care Quality Authority
core
Equity in Quality Mathematics Education: A Global Perspective
, 2010 Inequities in mathematics education at the global level are likely to filter into the national system and eventually into the classroom because of the hierarchical nested nature of the global mathematics education system.
Murad Jurdak, Jurdak M.
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Высшее образование в России, 2016 The paper analyzes the state of an interaction between a HEI and employers in the context of education modernization, reveals the causes why the social partnership between higher school and the labor market continues to be ineffective.
Yuriy N. Pak +2 more
doaj
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Organization and Quality in School Education
Procedia - Social and Behavioral Sciences, 2015 AbstractThe different approaches of educational institution analysis lead to a fundamental question: how the school may be able to meet the challenges of the economic and social framework continues to present? The interaction between educational institution with the territory and the social context can be effective if the school is able to analyze the ...
openaire +3 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Frontiers in EducationPurposeThe objective of this research is to compile a thorough review of existing literature, highlighting how artificial intelligence and personalized learning have shaped emerging research opportunities.Research methodologyThis study employs the PRISMA
Maryam Ikram +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source