Results 51 to 60 of about 1,297,185 (290)

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

open access: yesAdvanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding   +10 more
wiley   +1 more source

A duration analysis of CONALEP (Mexico's National Technical Professional School) [PDF]

open access: yes
Mexico's National Technical Professional School (Colegio Nacional de Educaci?n Profesional T?cnica, CONALEP) is the largest technical education system in the country. CONALEP serves low-income students at the upper-secondary school level in Mexico. Using
Lopez-Acevedo, Gladys
core  

Gram‐Scale Synthesis of Hafnium‐Rich Carbon Dots for Preclinical Computed Tomography Imaging Across Various Systems

open access: yesAdvanced Science, EarlyView.
Hafnium (Hf)‐rich carbon dots (Hf‐rCDs) with high metal content (40.7%) and robust batch production capacity (>2 g per batch) are synthesized via a facile air‐assisted pyrolysis method. In vivo CT imaging demonstrates outstanding performance of Hf‐rCDs across multiple physiological systems and enables high‐resolution visualization of swine cervical ...
Shuo Li   +11 more
wiley   +1 more source

Evaluating the effects of labour market reforms at the margin on unemployment and employment stability: the Spanish case. [PDF]

open access: yes
This study analyses the effects on unemployment and the quality of employment of the Spanish labour market reform in 2001 for the most important age groups.
Arellano, F. Alfonso
core   +3 more sources

Enhancing the Public Provision of Education: The Economics of Education Reform in Developing Countries [PDF]

open access: yes
The paper argues that a comprehensive evaluation of education reform in particular in developing countries needs considering the triangle’ quality-quantity-equity of educational policies in the short, medium and long term in a broader context than the ...
Rossana Patrón
core   +3 more sources

East Meets West: A Multisite Validity Study of the China Medical Professionalism Inventory

open access: yesPerspectives on Medical Education
Introduction: The characteristics of medical professionalism (MP) vary across cultural contexts. Professionalism constructs and MP tools currently rely on Western cultural perspectives.
Honghe Li   +7 more
doaj   +1 more source

Family Engagement and Education: A Research Scan and Recommendations [PDF]

open access: yes, 2014
In September 2012, The Heinz Endowments asked the Annenberg Institute for School Reform (AISR) at Brown University to conduct a research scan of family engagement, leadership, and organizing work related to education happening in Pittsburgh, as a part of
Joanne Thompson   +4 more
core  

Highly Sensitive and Temperature‐Insensitive Stretchable Strain Sensor with Microcrack‐Engineered Architecture

open access: yesAdvanced Science, EarlyView.
This study proposes a stretchable strain sensor that demonstrates a high gauge factor of 2.3 × 104 and excellent linearity (R2 = 0.98), while maintaining temperature insensitivity under applied strain. This performance is achieved through a microcrack architecture formed by stacking a brittle, low‐resistance material with a stretchable, high‐resistance
Yu Kato   +4 more
wiley   +1 more source

Seismic vulnerability analysis of single-story steel industrial building considering the enclosure structure

open access: yesJournal of Asian Architecture and Building Engineering
Earthquakes are severe hazards in seismic-prone areas, causing significant damage and casualties. Single-story steel industrial buildings are widely used for their high strength and durability, yet the impact of enclosure structures on their seismic ...
Yuhang Li   +4 more
doaj   +1 more source

From Scale to Quality: Experiences and Challenges in Teacher Education in China

open access: yesECNU Review of Education, 2019
Purpose: This essay examines the history of China’s teacher education policies, summarizes the Chinese experience of teacher education reform, and frames the major challenges facing teacher education reform in China today.
Bin Zhou
doaj   +1 more source

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