Results 121 to 130 of about 1,764,504 (269)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Cultural Integration through Foreign Languages Study (18th - 20th Centuries)

open access: yesStyles of Communication, 2013
A historical study on the penetration of French language in Romanian culture and the important role of education in spreading this language undoubtedly contributes to a better understanding of the beginnings of Romania’s opening to the West and to its ...
Viorica Păuş, Mirela Lazăr
doaj  

Exclusion and neoliberalism in the education system: socio-educational intervention strategies for an inclusive education system

open access: yes, 2018
Not only numerous academic and empirical studies recognise the educational factor as decisive on life and work trajectories, but also its integrating potential and role in the promotion of social cohesion are widely acknowledged. The diversity of current societies, the economic situation and the impact of neoliberal policies represent new challenges ...
Martínez Virto, Lucía   +1 more
openaire   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Analysing the sentiments about the education system trough Twitter. [PDF]

open access: yesEduc Inf Technol (Dordr), 2023
Mouronte-López ML   +2 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

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