Results 151 to 160 of about 2,246,833 (341)

Generative AI in Modern Education Society [PDF]

open access: yesarXiv
Transitioning from Education 1.0 to Education 5.0, the integration of generative artificial intelligence (GenAI) revolutionizes the learning environment by fostering enhanced human-machine collaboration, enabling personalized, adaptive and experiential learning, and preparing students with the skills and adaptability needed for the future workforce ...
arxiv  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Human-Centric eXplainable AI in Education [PDF]

open access: yesarXiv
As artificial intelligence (AI) becomes more integrated into educational environments, how can we ensure that these systems are both understandable and trustworthy? The growing demand for explainability in AI systems is a critical area of focus. This paper explores Human-Centric eXplainable AI (HCXAI) in the educational landscape, emphasizing its role ...
arxiv  

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