Results 161 to 170 of about 2,246,833 (341)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Estonian education system vs Spanish education system

open access: yes, 2018
When Estonia regained its independence from the Soviet regime, and as a consequence of the reform of its educational system, taking as a reference what they did in their neighbouring country Finland. Some analysts have defined it as the educational miracle in Estonia, being ratified for the results achieved in the PISA reports.
Ibáñez López-Quintana, Lidia   +1 more
openaire   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Exclusion and neoliberalism in the education system : socio-educational intervention strategies for an inclusive education system

open access: yes, 2018
Not only numerous academic and empirical studies recognise the educational factor as decisive on life and work trajectories, but also its integrating potential and role in the promotion of social cohesion are widely acknowledged. The diversity of current societies, the economic situation and the impact of neoliberal policies represent new challenges ...
Martínez Virto, Lucía   +1 more
openaire   +3 more sources

Exploring the social accountability challenges of nursing education system in Iran. [PDF]

open access: yesBMC Nurs, 2023
Ezzati E   +5 more
europepmc   +1 more source

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