TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo+11 more
wiley +1 more source
RESEÑA de: Green, A.; Wolf, A. y Leney, T. Convergence and Divergence in European Education and Training Systems. London: Institute of Education, 1999 [PDF]
María José García Ruíz
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Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno+12 more
wiley +1 more source
Exploring workplace mental health: educator perspectives and factors in the medical education system - a mixed method study. [PDF]
Keshmiri F.
europepmc +1 more source
Enhancing Statistics Education with Expert Systems: More than an Advisory System [PDF]
Laksita Barbara, L William
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Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu+12 more
wiley +1 more source
Competence by Design: The Role of High-Stakes Examinations in a Competence Based Medical Education System. [PDF]
Bhanji F+6 more
europepmc +1 more source
The Video System Used in Medical Education in the ENT Field
Kazutomo Kitajima+6 more
openalex +2 more sources
Building an Internet-Based Learning Environment in Higher Education: Learner Informing Systems and the Life Cycle Approach [PDF]
Zeynep Onay
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