Results 251 to 260 of about 1,731,831 (299)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

A Novel Education System to Createcustomized Primary Palliative Care Curricula for Training Programs. [PDF]

Am J Hosp Palliat Care
El-Sourady M, Martin S, Carroll T.
europepmc   +1 more source

Does the education system matter? Exploring in-depth joint school attendance, hazardous and non-hazardous activities in artisanal and small-scale mining in the Democratic Republic of the Congo. [PDF]

Heliyon
Murhi Mihigo I, Vermeylen G, Munguakonkwa B.   +2 more
europepmc   +1 more source

The Traditional System of Qur’anic Education in Northern Nigeria (Tsangaya): Recipe For A Feasible and Sustainable Reform

Ahmad Shuib Yahya, Aliyu Yunus Muhammad, Mustapha Ahmad, Shehu Dahiru Fagge   +3 more
openalex   +2 more sources

Advancing Embedded Systems Education: A Pedagogical Programming Framework for Smart System and Control Applications

Mbadiwe S. Benyeogor, Andrew O. Benyeogor, K. A. Olaiya, Prosper Agumey   +3 more
openalex   +2 more sources

REFORMING THE EUROPEAN DOCTORAL EDUCATION SYSTEM IN THE CONTEXT OF FORMATION OF GENERIC COMPETENCES

Наталя Дерстуганова
openalex   +1 more source

Personalized Learning Systems Using AI Enhancing Adaptive Education

D R Janardhana, Hajira Arif, Harshitha Bhat U, T Rukmini, Harish Hanumanthappa, Vidya Gaikwad   +5 more
openalex   +2 more sources

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Embedded systems education

ACM SIGBED Review, 2014
The embedded systems world has radically changed since the first Embedded Systems Design Master studies were proposed. The spectrum of application areas has increased and the whole industrial ecosystem is changed, having SMEs emerged as major players.
Mariagiovanna Sami, Miroslaw Malek, Umberto Bondi, Francesco Regazzoni   +3 more
openaire   +1 more source