Results 91 to 100 of about 4,758,137 (365)

Communication technologies and education: Lessons in the potential of innovation [PDF]

open access: yes, 1997
The evaluation of initiatives in using new forms of technology to enhance teaching and learning will raise awareness of the need for a structured and principled approach to the introduction of innovative methods.
Norman, Nigel
core   +4 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Beyond “appropriate” technology. Mobilizing education for development [PDF]

open access: yes, 2010
Having established that technology mediated instruction of some kind\ud has potential and a valuable role to play in education for on the move and remote\ud area learners the paper looks at practice as documented and suggests that social\ud and cultural ...
Hewling, Anne, Sesnan, Barry
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Flipped Classroom for Doctoral Students: Evaluating the Effectivness

open access: yesВысшее образование в России, 2019
The demand of Industry 4.0 for creative researchers able to adopt to the changing world and think out of the box puts forward the question of education technologies used to prepare such specialists.
K. N. Volchenkova
doaj   +1 more source

Harnessing technology review 2008. The role of technology and its impact on education. Full report. [PDF]

open access: yes, 2008
This is the second review of the use and impact of ICT in the education system following the publication of the Government's e-Strategy for education, known as Harnessing Technology.
Davies, Steve, Pittard, Vanessa
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The enhancement of technology education classroom practice in New Zealand [PDF]

open access: yes, 2001
This paper reports on a number of New Zealand technology education research studies undertaken over seven years by researchers in the Centre for Science and Technology Education Research centred upon examining and enhancing classroom practice.
Jones, Alister, Moreland, Judy
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

アクティブ・ラーニングに関する群馬高専の現状と取り組み [PDF]

open access: yes, 2019
Due to the accelerated progress of knowledge and information technology, as typified by artificial intelligence, education is required to acquire knowledge and skills; yet concurrently, cultivating the abilities of thought, judgment, and expression is ...
中島, 敏   +8 more
core  

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