Results 51 to 60 of about 3,909,485 (258)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Family interaction patterns as correlates of bullying behaviour among in-school adolescents in Kwara State

Revista de Investigación en Psicología
The involvement of parents in different roles in life sometimes affects their communication with their children, which can affect the bullying behaviour of adolescents in school.
Mulikat Ladi Abdulqadir Mustapha, Shuaib Abolakale Muhammed, Muhinat Bolanle Bello, Faysol Aderibigbe Abisoye   +3 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The evidence base on lifelong guidance (Brief Summary) [PDF]

, 2014
THE PURPOSE OF THIS EVIDENCE GUIDE is to present the existing international research base on the impact of lifelong guidance, including its educational outcomes, economic and employment outcomes, and social outcomes. The guide has been prepared for ELGPN
Hooley, Tristram
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Ensuring quality in career guidance: a critical review [PDF]

, 2018
In rapidly changing employment markets, career guidance has a vital role to play in supporting people in navigating transitions between education and employment across the lifespan.
Rice, Suzanne, Hooley, Tristram, Rice, S, Hooley, T   +3 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Career construction model of adaptation: an empirical study among university students in Türkiye

Frontiers in Psychology
Grounded in the Career Construction Model of Adaptation (CCMA), this study examined the direct and indirect associations among self-esteem, cognitive flexibility, general self-efficacy, career adaptability, career choice status (whether students chose ...
Aşkay Nur Atasever, Metin Pişkin
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Marital conflict resolution through schema therapy and mutual behaviour analysis for enhanced self-differentiation in Kwara State

Frontiers in Sociology
IntroductionMarital conflict remains a persistent challenge among couples in Nigeria, often driven by deep-rooted maladaptive cognitive schemas, dysfunctional behavioural patterns, and poor self-differentiation.
Lateef Omotosho Adegboyega, Adeola Aminat Odebode, Samuel Kolawole Ajiboye, Alfred Olatayo Awoyemi, Segun Olayide Odutayo, Abdulrasaq Olatunji Balogun   +5 more
doaj   +1 more source