Results 51 to 60 of about 11,203,384 (195)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Maarif Vekâleti İhsaiyat Mecmuasına Göre 1925-1926 Ders Senesinde Balıkesir Hususi Mektepleri

Vakanüvis Uluslararası Tarih Araştırmaları Dergisi, 2018
Osmanlı Devletinin son yıllarında eğitim ve öğretim kurumlarının önemli bir bölümünü oluşturan yabancı okullar, azınlık okulları ve özel okullar, dönemin eğitim politikalarının değerlendirilmesi açısından azımsanamayacak bir yer tutar.
M. Serhan YÜCEL
doaj  

The Need for Better Attachment Bonds Between Institutional Caregivers and Children in Residential Care: A Systematic Review

Behavioral Sciences
Attachment is an emotional bond based on the first relationships formed between people. In the case of institutionalized children, it is more difficult to establish a secure attachment bond with an adult.
María-Jesús Martínez-Usarralde, Raquel Conchell, Mónica Villar, Lucía Pérez-Tabernero   +3 more
doaj   +1 more source

Contrasting mitochondrial diversity of European starlings (Sturnus vulgaris) across three invasive continental distributions

Ecology and Evolution, 2020
European starlings (Sturnus vulgaris) represent one of the most widespread and problematic avian invasive species in the world. Understanding their unique population history and current population dynamics can contribute to conservation efforts and ...
Louise Hart Bodt, Lee Ann Rollins, Julia M. Zichello   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Student–Teacher Communication in Digital Higher Education: Politeness, Implicature, and Institutional Interaction

Education Sciences
This study investigates the linguistic mechanisms of politeness and conversational implicature in digital classroom interactions at “1 Decembrie 1918” University of Alba Iulia (UAB), Romania.
Gabriel-Dan Barbulet, Andra-Iulia Ursa, Valentin Todescu   +2 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source

THE CONSEPT AND ITS IMPLEMENTATION OF INDONESIAN LEGISLATIVE ELECTIONS BASED ON THE PANCASILA DEMOCRACY PERSPECTIVE

Yustisia, 2019
Indonesia’s democracy system was built on the basis and the strength of Pancasila, which did not favor the excessive desires of individual negotiations (liberalism) neither absolute state domination, non-liberalism, namely direct and indirect democracy ...
Franciscus Xaverius Wartoyo, Benyamin Tungga   +1 more
doaj   +1 more source

History of Educational Technology – Editorial

Journal of Interactive Media in Education, 2020
This collection brings together four articles which examine both broad approaches to the history of educational technology and more specific analysis of particular technologies.
Martin Weller
doaj   +1 more source