Results 41 to 50 of about 11,255 (215)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

EFFICIENCY OF EDUCATIONAL INNOVATIVE TECHNIQUES IN TEACHING FINANCIAL AND ECONOMIC DISCIPLINES (BASED ON SOCIAL RESEARCH)

Sovremennye Issledovaniâ Socialʹnyh Problem, 2013
Importance of the presented study consists in need of the introduction innovation educational technology when teaching in high educational institutions.
Irina Konstantinovna Bitkina
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

INNOVATIVE DEVELOPMENT OF EDUCATIONAL SYSTEMS: CATEGORICAL MEANING [PDF]

Krymskij Naučnyj Vestnik, 2017
This article discusses the concept of «development», «innovation» and «innovation development» in relation to the educational systems, as to create a new conceptual framework for quality education.
Natalia Tretyak
doaj  

Innovative Strategies in the Educational Field: Analysis of the Systematic Mapping of Literature

Proceedings, 2018
Educational innovation appears as a pending issue in the agendas of educational institutions at the international level. Current educational policies highlight the importance of educational innovation as a key element for improving educational quality ...
Leticia Nayeli Ramírez-Ramírez, María Soledad Ramírez-Montoya   +1 more
doaj   +1 more source

Data-driven iterative refinements to educational development services: directly measuring the impacts of consultations on course and syllabus design

To Improve the Academy, 2022
Evidence-based practice in educational development includes leveraging data to iteratively refine center for teaching and learning (CTL) services.
Chad Hershock, Emily Daniels Weiss, Jacqueline Stimson, Jessica Harrell, Katie Walsh, Laura Ochs Pottmeyer, Marisella Rodriguez, Sophie le Blanc   +7 more
doaj   +2 more sources

Innovative kinesiology education as a criterion and predictor of innovative education

Inovacije u nastavi
Agreement with living conditions also implies compliance with the increasingly dramatic changes to which the civilization, society, and the people are exposed. The imperative response of society and civilization to changes that are inevitable but evident, with even clearer and more predictable consequences, must be the best in order to be good enough ...
Ivan Prskalo, Danimir Mandić, Vladan Pelemiš   +2 more
openaire   +2 more sources

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Formal, non-formal and informal education and innovation: Innovating to educate and educating to innovate

, 2023
Este documento analisa a relação entre a experiência educacional e a pessoa inovadora, e estuda a influência desta experiência no desenvolvimento de competências e capacidades de inovação nas pessoas entrevistadas. A discussão é baseada numa abordagem qualitativa, através de dez entrevistas com pessoas definidas como inovadoras, localizadas em empresas
Soto Kiewit, Luis Diego, Segura Jiménez, Alexis, Navarro Rojas, Óscar, Cedeño Rojas, Sara, Medina Díaz, Rebeca   +4 more
openaire   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source