Results 41 to 50 of about 138,572 (263)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Designing a Phenomenon-Based Learning Boxset to foster scientific literacy in under-resourced schools

Social Sciences and Humanities Open
Scientific literacy is essential for equipping students with critical thinking and problem-solving skills. However, under-resourced schools often rely on outdated instructional methods and lack inquiry-based learning materials.
Chulida Hemtasin, Chanidaporn See-Onjan, Wisarut Payoungkiattikun   +2 more
doaj   +1 more source

A three wave longitudinal study of school innovation climate and entrepreneurship teachers’ acceptance to technology: Moderating role of knowledge sharing and knowledge hiding

Frontiers in Psychology, 2022
Entrepreneurship and business school teachers must extensively use technological and innovative tools to increase the efficacy of their instructional methods.
Rudsada Kaewsaeng-on, Suhaib Khaled AL-Takhayneh, Farooq Ahmed Jam, Bang-Lee Chang, Mahir Pradana, Saqib Mahmood   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

INNOVATIVE DEVELOPMENT OF EDUCATIONAL SYSTEMS: CATEGORICAL MEANING [PDF]

Krymskij Naučnyj Vestnik, 2017
This article discusses the concept of «development», «innovation» and «innovation development» in relation to the educational systems, as to create a new conceptual framework for quality education.
Natalia Tretyak
doaj  

Data-driven iterative refinements to educational development services: directly measuring the impacts of consultations on course and syllabus design

To Improve the Academy, 2022
Evidence-based practice in educational development includes leveraging data to iteratively refine center for teaching and learning (CTL) services.
Chad Hershock, Emily Daniels Weiss, Jacqueline Stimson, Jessica Harrell, Katie Walsh, Laura Ochs Pottmeyer, Marisella Rodriguez, Sophie le Blanc   +7 more
doaj   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Innovative kinesiology education as a criterion and predictor of innovative education

Inovacije u nastavi
Agreement with living conditions also implies compliance with the increasingly dramatic changes to which the civilization, society, and the people are exposed. The imperative response of society and civilization to changes that are inevitable but evident, with even clearer and more predictable consequences, must be the best in order to be good enough ...
Ivan Prskalo, Danimir Mandić, Vladan Pelemiš   +2 more
openaire   +2 more sources

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Formal, non-formal and informal education and innovation: Innovating to educate and educating to innovate

, 2023
Este documento analisa a relação entre a experiência educacional e a pessoa inovadora, e estuda a influência desta experiência no desenvolvimento de competências e capacidades de inovação nas pessoas entrevistadas. A discussão é baseada numa abordagem qualitativa, através de dez entrevistas com pessoas definidas como inovadoras, localizadas em empresas
Soto Kiewit, Luis Diego, Segura Jiménez, Alexis, Navarro Rojas, Óscar, Cedeño Rojas, Sara, Medina Díaz, Rebeca   +4 more
openaire   +1 more source