Results 111 to 120 of about 1,575,689 (300)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Managing comprehensive educational institution in modern conditions [PDF]

open access: yes, 2015
Сьогодення вимагає нових підходів до управління сучасним загальноосвітнім навчальним закладом.Особливо актуальною залишається проблема підготовки керівників ЗНЗ, які, на жаль, не завжди мають спеціальну менеджерську освіту.
Alendar, Nadia I.   +1 more
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Local Control: An Educational Model of Private Enforcement of Public Rules [PDF]

open access: yes
We study a society of agents where individual incentives conflict with collective ones and thus individual utility maximization leads to inefficient outcomes.
Huck, S., Kosfeld, M.
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Management of professional training in the conditions of university college: theoretical aspect [PDF]

open access: yes, 2016
Досліджено теоретичні основи управління підготовкою фахівців в умовах вищого навчального закладу на засадах середовищного підходу. Встановлено, що середовищний підхід, завдяки своїм сутнісним особливостям, забезпечує опосередковане, через проектування ...
Братко, Марія Василівна
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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