Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Psychometric evaluation of the Chinese version of the Educational Leadership Scale for Nursing Students: a quantitative cross-sectional design. [PDF]
Yu X, Wang X, Wang X.
europepmc +1 more source
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown +6 more
wiley +1 more source
Psychometric properties of the educational leadership scale for nursing students. [PDF]
Jalali A +5 more
europepmc +1 more source
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen +7 more
wiley +1 more source
Performing womanhood in schools: a feminist phenomenological investigation of female teachers' psycho-social health experiences and implications for educational leadership in Turkey. [PDF]
Iş E.
europepmc +1 more source
TRUST IN EDUCATIONAL LEADERSHIP
The study examines how trust is manifested in principals’ co-operation with their own employees in the implementation of local development work. The research question is: How is trust expressed in principals’ co-operation with employees and leaders? The study is based on interviews with three principals in a medium-sized municipality.
openaire +2 more sources
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
Transforming nursing education: the power of educational leadership in optimizing time management and competency. [PDF]
Amin SM +7 more
europepmc +1 more source

