Results 151 to 160 of about 31,467 (267)

Exploring the Icarus Paradox in Indonesia's Specialist Medical Education System Using the Public Perspective From Online Media: Convergent Mixed Methods Study. [PDF]

JMIR Med Educ
Hamsal M.
europepmc   +1 more source

REGγ Suppresses Ferroptosis and Induces Drug Resistance by Degrading WDR6 in Chondrosarcoma

Advanced Science, EarlyView.
Here, we identified REGγ as a susceptibility factor in chondrosarcoma. Our study demonstrates that abnormally activated REGγ‐20S proteasome promotes chondrosarcoma development and progression. Further validation in animal models revealed that blocking REGγ function induced ferroptosis, suppressed malignant progression of chondrosarcoma, and uncovered a
Fanrong Liu, Shihui Shen, Dongxia Li, Peilin Shi, Jiaming Xu, Tongxin Lv, Yingying Du, Jingwei Zhang, Bo Yang, Hansen Chen, Zhuoya Peng, Wenjie Ren, Lu Zhang, Sheng Cheng, Tongjin Yin, Wencai Sheng, Lei Li, Juan Wu, Qingcheng Yang, Shuogui Xu, Wei Zheng   +20 more
wiley   +1 more source

ChatGPT-Assisted Patient Counselling in Chronic Suppurative Otitis Media (CSOM): A Pilot Feasibility Study. [PDF]

J Otol
Regin W.
europepmc   +1 more source

Features of Creation of Informationy-Communication Technologies of Study for Graphic Preparation of Future Specialist of Technical Industry

, 2013
У статті розглянуто особливості педагогічної взаємодії науково-педагогічного працівника кафедри графічної підготовки і майбутнього фахівця вищого технічного навчального закладу в системі «науково-педагогічний працівник-комп’ютер-майбутній фахівець» під ...
Koziar M. M., Козяр М. М.
core  

Integrative Omics Analysis Reveals the Regulation of Hypoxia Tolerance in Large Yellow Croaker (Larimichthys crocea) via the Lipoic Acid Synthase (lias) Gene

Advanced Science, EarlyView.
Lipoic acid synthase (lias) can regulate α‐KG levels through lipoylation, thereby negatively regulating HIF‐1α protein levels via PHD under hypoixa. The Hap2 allele of lias exhibits lower expression levels than Hap1, leading to the accumulation of more HIF‐1α protein and thereby enhancing hypoxia tolerance. ABSTRACT Hypoxia stress seriously affects the
Jie Ding, Songpeng Jia, Ran Meng, Xuelei Wang, Xiongfei Wu, Weiliang Shen, Yibo Zhang, Junquan Zhu   +7 more
wiley   +1 more source

Slc44a2 Deficiency Unveils an IFN‐I–Dependent Feedback Control of pDC Egress

Advanced Science, EarlyView.
Working model of SLC44A2‐mediated maintenance of pDC homeostasis. This model illustrates two central mechanisms by which SLC44A2 regulates pDC homeostasis: (1) SLC44A2 limits IFN‐I production by exporting amino acids (T, N, Q), thereby preventing spontaneous pDC activation.
Ruiqun Chen, Tao Wu, Zhen Shi, Ravi Kumar Verma, Linlin Sheng, Lei Tao, Mingming Yang, Yuchen Wang, Conggang Zhang, Hao Fan, Li Wu, Ligong Chen   +11 more
wiley   +1 more source

Development and Validation of an Educational Podcast on Intestinal Ostomy Care: Methodological Study. [PDF]

Nurs Open
do Nascimento RM, da Silva IP, Freitas LS, de Morais ILA, Gonçalves AAC, Araújo ROE, Costa IKF.   +6 more
europepmc   +1 more source

A study to develop and evaluate a multi-media resource in palliative and end-of-life care for specialist palliative care and learning disability services : promoting collaborative working

, 2012
Background The literature highlights concerns regarding the quality of palliative care offered to people with learning disabilities (Michael, 2008). It is also recognised that better collaboration between learning disability and specialist palliative ...
McLaughlin, Dorry
core  

Real‐Time in Vivo Monitoring of Circulating Endometrial Cells: Uncovering Systemic Dissemination and Temporal Fluctuations in Endometriosis

Advanced Science, EarlyView.
A dual‐color pseudo‐menstrual mouse model enables real‐time tracing of circulating endometrial cells (CECs) from uterine and ectopic sources. The study reveals menstrual‐phase‐dependent, burst‐like CEC release, distinct postoperative behaviors of different CEC origins, and a potential association with prolactin fluctuations, providing an in vivo ...
Shang Wang, Chenyu Hou, Buyun Li, Hongyan Cheng, Xue Ye, Honglan Zhu, Yanmin Li, Rui Chen, Sihan Dong, Yi Li, Huiping Liu, Chen Zhang, Rui Zhang, Hongyi Hou, Xunbin Wei, Xiaohong Chang   +15 more
wiley   +1 more source

Quality and reliability of aortic dissection-related health information on TikTok and Bilibili: a cross-sectional content analysis study. [PDF]

J Thorac Dis
Fang L, Yin J, Dai T, Li X.
europepmc   +1 more source