Results 81 to 90 of about 4,903,337 (345)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Novos paradigmas na educacão online com a aprendizagem aberta [PDF]

open access: yes, 2007
This paper aims to discuss important concepts related to online education which bring a new educational paradigm: open learning through free learning materials and technologies.
Okada, Alexandra
core  

Integration of business into university educational ecosystems

open access: yesВестник университета
The emergence of the platform economy and the development of digital infrastructure in the XXI century has led to significant changes in higher education. Professional knowledge can now be acquired not only through classical universities but also through
Yu. I. Rishko   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Enhanced Data Integration for LabVIEW Laboratory Systems

open access: yes, 2013
Integrating data is a basic concern in many accredited laboratories that perform a large variety of measurements. However, the present working style in engineering faculties does not focus much on this aspect. To deal with this challenge, we developed an
Ionita, Anca Daniela   +3 more
core   +1 more source

Uczenie się i nauczanie słownictwa języka polskiego 
za pomocą technologii 
informacyjno­komunikacyjnych. 
Stan realizacji projektu 
„Polish Your Polish/(Un)Polish Your Russian” na KU Leuven (Belgia)

open access: yesPostscriptum Polonistyczne, 2020
The article presents and evaluates lexical exercises and glottodidactic tasks presented on an educational platform Polish Your Polish – (Un)Polish Your Russian (KU Leuven, Belgia).
Sandra Toffel, Kris Van Heuckelom
doaj  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Online resource platform for mathematics education

open access: yes2014 IEEE Frontiers in Education Conference (FIE) Proceedings, 2014
Engineering education is facing many challenges: a decline in core mathematical skills; lowering entry requirements; and the diversity of the student cohort. One approach to confronting these challenges is to make subject content appropriate to the communication styles of today's student.
Llorens, Marisa   +2 more
openaire   +4 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

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