Results 81 to 90 of about 3,839,343 (357)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Independent Educational Evaluations as Issues of Dispute in Special Education Due Process Hearings [PDF]
, 2019 This study examined the pertinent details and outcomes of special education due process hearings (n = 100) that addressed independent educational evaluations as an issue of dispute in a 14-state sample.
Blackwell, William H, Gomez, Mertie
core +1 more source
Libraries, Language, and Change: Defining the Information Present [PDF]
, 1998 Changes in the information world are resulting in new concepts of resource sharing, new practices in the management of library resources, and an expanding role for libraries in the educational process.
Billings, Harold
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
OPTIMIZATION AND EDUCATIONAL PROCESS IN HIGHER EDUCATIONAL INSTITUTIONS SPIRITUAL [PDF]
, 2017 Modification in Church ministers′ training require a new approaches and quality that meet the fundamental European Union and the Bologna process provisions and the common European education space, including competency approach to spiritual education ...
Popovych, V.
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Mediating Role of Job Satisfaction Between Leadership and Organizational Performance and the Moderating Effect of Educational Context [PDF]
Educational Process: International JournalBackground/purpose. Leadership behaviors correlate with job satisfaction, which is supposed to have impact on overall organizational performance. This study aimed to establish a model to explain organizational performance by determining the relational ...
Fahrettin Gılıç , Sedat Kanadlı , Yüksel Gündüz , Yusuf İnandı
doaj +1 more source
Educational Process and Personality of the Educator [PDF]
Acta Technologica Dubnicae, 2012 Abstract The paper is focused on the personality of an educator and the demands placed on him/her.
Lenka Pasternáková +1 more
openaire +1 more source
The use of student development to improve the educational process [PDF]
, 2017 В статье рассматривается один из экспериментальных методов, который заключается в непосредственном вовлечение студентов в разработку учебных ...
Тарасьев, А. А. +1 more
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