Results 141 to 150 of about 424,348 (309)

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Kompetencetilegnelse af klinisk lederskab i sygepleje

open access: yesTidsskrift for Professionsstudier
Clinical leadership is a central and dominant educational concept in nursing education expressed in learning objectives. However, we know very little about how clinical leadership takes shape in clinical practice and how it is acquired, which we explore
Camilla Bernild   +3 more
doaj  

QUALIFICATIONS OF HIGHER EDUCATION AND PROFESSIONAL QUALIFICATIONS: HARMONIZATION WITH EFFORTS

open access: yesВысшее образование в России, 2018
The paper focuses on the topical problem of harmonization of professional and educational qualifications. Based on the analysis of the international practice (US experience), the author considers the attempts to couple professional standards and federal state educational standards and shows their inadequacy. The paper dwells on the peculiarities of the
openaire   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

The Educational Qualifications of Health Officers [PDF]

open access: yesAmerican Journal of Public Health and the Nations Health, 1939
openaire   +2 more sources

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