Results 51 to 60 of about 851,887 (336)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Educational Attainment and Employment Outcome of Survivors of Pediatric CNS Tumors in Switzerland—A Report from the Swiss Childhood Cancer Survivor Study

Children, 2022
Background: Childhood cancer survivors diagnosed with a central nervous system (CNS) tumor are at risk for educational and vocational challenges. This study compared educational attainment and employment outcome in survivors of CNS tumors to survivors of
Maria Otth, Gisela Michel, Nicolas U. Gerber, Ana S. Guerreiro Stücklin, André O. von Bueren, Katrin Scheinemann, on behalf of the Swiss Pediatric Oncology Group (SPOG)   +6 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Myths and Justifications of Sex Segregation in Higher Education: VMI and The Citadel [PDF]

, 1997
Access to higher education, particularly to the specialized and elite education that is part of the tracking system leading to prestigious and highly remunerative positions, is a measure of equality.
Epstein, Cynthia Fuchs
core   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Educational choice in Australia

Revue Internationale d’Éducation de Sèvres
Australia provides substantial opportunities to engage in educational choices. These exist primarily in household choice of school, and choice of study pathway in secondary school.
Laura B. Perry
doaj   +1 more source

The “Diplomado para docentes de apoyo a la inclusión”: training as a factor of empowerment in El Salvador

Ricerche di Pedagogia e Didattica, 2016
The Department of Educational Sciences of the University of Bologna has implementing an international cooperation project in El Salvador (2009-2014), in partnership with the local Ministry of Education to support the schooling inclusion.
Luigi Guerra, Arianna Taddei
doaj   +1 more source

Introspection into Indian School Education System

International Journal of Management and Humanities, 2020
This article probes deeper into the Indian school education system and states that there is a deep rooted systemic flaws in the pedagogical planning and execution. It reviews and discuss on policy and regulatory changes or reforms needed in the existing system.
openaire   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source