Results 71 to 80 of about 150,804 (267)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Nano- and Submicron-Sized TiB₂ Particles in Al–TiB₂ Composite Produced in Semi-Industrial Self-Propagating High-Temperature Synthesis Conditions

Metals
This paper investigates the structure and phase composition of Al–TiB2 metal matrix composites prepared from the Al–Ti–B system powder using self-propagating high-temperature synthesis (SHS) in semi-industrial conditions (the amount of the initial powder
Aleksey Matveev, Vladimir Promakhov, Nikita Schulz, Vladislav Bakhmat, Timur Turanov   +4 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Multidisciplinary Education Pathways to Attract High School Students Toward Research and Science

Education Sciences
This study reports the design, implementation, and descriptive evaluation of “Codici del Futuro”, a STEM-oriented education pathway developed by the Italian National Research Council (CNR) to promote students’ interest in science and awareness of ...
Giuseppe Chiazzese, Chiara Aliotta, Marco Russo, Maria Luisa Testa, Marco Arrigo, Mariella Farella, Dario La Guardia, Manuel Gentile, Davide Taibi, Giuseppe Città, Salvatore Perna, Giovanna Montana, Giovanni Perconti, Angela Bonura, Francesca Deganello   +14 more
doaj   +1 more source

Solar Multi-stage Refrigeration Systems on the Basis of Absorber with the Internal Evaporative Cooling [PDF]

Problems of the Regional Energetics, 2015
In the article, the developed schematics are presented for the alternative refrigeration systems and air-conditioning systems, based on the use of absorbing cycle and solar energy for the regeneration of absorbent solution.
Doroshenko A.V., Kirillov V.H., Antonova A.R., Liudnicky K.V.   +3 more
doaj  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Kinetic Aspects of Ethylene Glycol Degradation Using UV-C Activated Hydrogen Peroxide (H₂O₂/UV-C)

Molecules
Ethylene glycol (EG) is a contaminant in the wastewater of airports because it is commonly used in aircraft deicing fluids during the cold season in northern regions. Ethylene glycol by itself has relatively low toxicity to mammals and aquatic organisms,
Timur Fazliev, Mikhail Lyulyukin, Denis Kozlov, Dmitry Selishchev   +3 more
doaj   +1 more source

New Solutions for Solar Absorption Refrigeration Systems and Air Conditioning Systems [PDF]

Problems of the Regional Energetics, 2017
The mission of the research includes the following objectives: the development of new circuit decisions for the alternate refrigerating systems based on the use of an open absorptive circuit and on the use of solar energy for absorbent solution ...
Doroshenko A.V., Antonova A.R., Liudnicky K.V., Ivanova L.V.   +3 more
doaj